Centro de Salud Puerta de Madrid, Atención Primaria de, Madrid, Spain.
Clin Nutr ESPEN. 2021 Feb;41:10-12. doi: 10.1016/j.clnesp.2020.12.001. Epub 2020 Dec 24.
BACKGROUND & AIMS: Vitamin D is a fat-soluble vitamin whose main function in the body is the regulation of bone mineral metabolism. In the last two decades, there has been an intensive research for possible vitamin D benefits in non-skeletal health but as today it still remains unclear. The aim of this article is to review vitamin D metabolism and the natural sources to encourage lifestyle changes to avoid deficiency.
Universal screening for vitamin D deficiency is not warranted and it should only be done in cases with risk factors for vitamin deficiency. Vitamin D is measured in the body by determining 25-hydroxycholecalciferol; values below 20 ng/mL (50 nmol/L) are considered inadequate. The three sources of vitamin D are the ultraviolet sun radiation, diet and supplementation. The role of vitamin D supplementation out of the osteoporosis treatment and prevention still remain controversial. Healthy sun exposure and diet should be discussed with all patients with vitamin D deficiency and in general population in promoting health. The skin, through solar radiation, is the main source of vitamin D and provides 90% of the body's needs.
Changing lifestyle habits, encouraging a controlled sun exposure and proper vitamin D diet is a preventive strategy that should be applied in our daily practice to prevent osteoporosis and other diseases associated with low vitamin D.
维生素 D 是一种脂溶性维生素,其在体内的主要功能是调节骨骼矿物质代谢。在过去的二十年中,人们对维生素 D 在非骨骼健康方面的可能益处进行了深入研究,但至今仍不清楚。本文旨在回顾维生素 D 的代谢和天然来源,以鼓励生活方式的改变,避免维生素 D 缺乏。
普遍筛查维生素 D 缺乏症是没有必要的,只有在存在维生素缺乏症风险因素的情况下才应进行筛查。体内维生素 D 的测定通过测定 25-羟胆钙化醇来进行;低于 20ng/ml(50nmol/L)的值被认为是不足的。维生素 D 的三个来源是紫外线太阳辐射、饮食和补充剂。维生素 D 补充剂在骨质疏松症治疗和预防之外的作用仍存在争议。对于维生素 D 缺乏症患者和一般人群,应讨论健康的阳光暴露和饮食,以促进健康。皮肤通过太阳辐射是维生素 D 的主要来源,提供了人体 90%的需求。
改变生活习惯,鼓励适度的阳光暴露和适当的维生素 D 饮食是一种预防策略,应在我们的日常实践中应用,以预防骨质疏松症和其他与低维生素 D 相关的疾病。