Nag Falguni, Chatterjee Gobinda, Ghosh Arghyaprasun, De Abhishek
Department of Dermatology, Purulia Government Medical College, Purulia, West Bengal, India.
Department of Dermatology, IPGMER & SSKM Hospital, Kolkata, India.
Indian J Dermatol. 2020 Nov-Dec;65(6):495-499. doi: 10.4103/ijd.IJD_62_20.
A chronic leg ulcer (CLU) is a significant public health problem. It has various etiologies. Racial, familial, occupational, and social factors may also have an impact on the prevalence of different causes of leg ulcers. Though there are western data on the epidemiology of leg ulcer, similar data are largely unavailable from our part of the world.
We undertook a study in a tertiary care center in eastern India to determine the clinical and etiological pattern of patients with CLU.
Hundred consecutive patients presenting with CLU, fulfilling the criteria, were included after informed consent. Patients were subjected to proper history taking, clinical examination, routine blood test, and pus for culture and sensitivity test (where needed) along with Ankle Brachial Index (ABI).
Among the 100 patients, venous ulcer (34%) was predominant followed by arterial ulcer (14%), mixed arterial and venous ulcer (11%). History of smoking (56%) and obesity (BMI >25) (32%) were the common risk factors in leg ulcer patients. Fifty nine percent of the total CLU were infected and out of this, 86.4% showed growth of microorganisms. (39%) was the most commonly isolated organism, followed by (15%). Eleven (24.44%) clinically diagnosed venous ulcer patients showed significantly lower ABI (<0.9) and were diagnosed as mixed ulcer (a venous ulcer with a peripheral arterial disease).
Venous ulcer and mixed ulcer are the most common type of CLU.
慢性腿部溃疡（CLU）是一个重大的公共卫生问题。其病因多种多样。种族、家族、职业和社会因素也可能对不同病因的腿部溃疡患病率产生影响。尽管有关于腿部溃疡流行病学的西方数据，但在我们所在的地区，类似数据基本无法获取。
我们在印度东部的一家三级医疗中心开展了一项研究，以确定CLU患者的临床和病因模式。
在获得知情同意后，纳入了连续100例符合标准的CLU患者。对患者进行了详细的病史采集、临床检查、常规血液检查以及必要时的脓液培养和药敏试验，同时测量了踝臂指数（ABI）。
在这100例患者中，静脉性溃疡（34%）最为常见，其次是动脉性溃疡（14%）、动静脉混合性溃疡（11%）。吸烟史（56%）和肥胖（BMI>25）（32%）是腿部溃疡患者常见的危险因素。所有CLU患者中有59%发生感染，其中86.4%有微生物生长。（39%）是最常分离出的微生物，其次是（15%）。11例（24.44%）临床诊断为静脉性溃疡的患者ABI显著降低（<0.9），被诊断为混合性溃疡（伴有外周动脉疾病的静脉性溃疡）。
静脉性溃疡和混合性溃疡是CLU最常见的类型。
