Respiratory Sub-Specialty Group, Occupational Therapy Central Organization Committee, Hospital Authority, Hong Kong SAR.
Occupational Therapy Department, Prince of Wales Hospital, Hospital Authority, Hong Kong SAR.
Int J Chron Obstruct Pulmon Dis. 2021 Jan 15;16:91-100. doi: 10.2147/COPD.S283769. eCollection 2021.
The Manchester Respiratory Activities of Daily Living Questionnaire (MRADLQ) is a valid and reliable tool measuring the functional level of patients with COPD in multidimensional aspects. However, a local validation of the questionnaire is lacking in Hong Kong.
To develop a Chinese version of MRADLQ with pictorial enhancement (C-MRADLQ) and study its reliability and validity.
A total of 238 patients suffering from COPD were recruited from nine public hospitals and five Nurse and Allied Health Respiratory Clinics by convenient sampling. A total of 64 patients with normal spirometry results and no previous clinical diagnosis of COPD were invited to complete the C-MRADLQ for comparison and examination of its validity. Ten out of 302 patients were re-assessed with the C-MRADLQ after one week by the same rater for test-retest reliability. The C-MRADLQ was correlated with spirometry result, COPD classifications and groups by Global Initiative for Chronic Obstructive Lung Disease (GOLD), the modified Medical Research Council Dyspnea Scale (mMRC Dyspnea Scale), COPD Assessment Test (CAT), Chinese Version of the Shortness of Breath Questionnaire (C-SOBQ), number of admission and the ADO index.
The C-MRADLQ shows good test-retest reliability as indicated by an intra-class correlation coefficient value of 0.975. It is significantly correlated with COPD stage, COPD group, SOBQ score, CAT score, mMRC, ADO index, spirometry results, and number of admissions. The SOBQ score, number of admissions, FEV1/FVC, and COPD group could significantly predict the total C-MRADLQ score. A total of 67.9% of participants' mMRC levels were correctly classified by using the C-MRADLQ total score. The agreement of the original and new versions of questions 20 and 21 of C-MRADLQ was 97.3% and 90.1%, respectively.
The pictorial version of the C-MRADLQ is a validated and reliable functional assessment tool to measure functional status among patients with COPD in the Chinese population.
曼彻斯特呼吸日常活动问卷（MRADLQ）是一种有效的、可靠的工具，可以从多个维度测量 COPD 患者的功能水平。然而，该问卷在香港尚未经过本土化验证。
开发一种带有图片增强功能的中文版 MRADLQ（C-MRADLQ），并研究其信度和效度。
通过便利抽样，从九所公立医院和五所护士和联合健康呼吸诊所共招募了 238 名患有 COPD 的患者。此外，共邀请了 64 名肺功能正常且无 COPD 既往临床诊断的患者完成 C-MRADLQ，以进行比较并检验其有效性。302 名患者中的 10 名在一周后由同一位评估者进行了 C-MRADLQ 的重测，以评估其测试-重测信度。C-MRADLQ 与肺功能结果、慢性阻塞性肺疾病全球倡议（GOLD）分类、改良呼吸困难量表（mMRC 呼吸困难量表）、COPD 评估测试（CAT）、中文版呼吸困难问卷（C-SOBQ）、住院次数和 ADO 指数相关。
C-MRADLQ 显示出良好的测试-重测信度，组内相关系数值为 0.975。它与 COPD 分期、COPD 组、SOBQ 评分、CAT 评分、mMRC、ADO 指数、肺功能结果和住院次数显著相关。SOBQ 评分、住院次数、FEV1/FVC 和 COPD 组可显著预测 C-MRADLQ 总分。C-MRADLQ 总分可正确分类 67.9%的患者的 mMRC 水平。C-MRADLQ 问题 20 和 21 的原始和新版本之间的一致性分别为 97.3%和 90.1%。
中文版 C-MRADLQ 是一种经过验证和可靠的功能评估工具，可用于测量中国人群中 COPD 患者的功能状态。
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