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持续皮下注射奥曲肽成功治疗一名接受血液透析的成年发病的胰岛细胞增殖症患者。

Successful treatment of adult-onset nesidioblastosis by continuous subcutaneous octreotide infusion in a patient on hemodialysis.

作者信息

Kato Rina, Nishimura Akihiro, Matsumura Kimio, Kikuno Shota, Nagasawa Kaoru, Mori Yasumichi

机构信息

Department of Endocrinology and Metabolism Toranomon Hospital Minato-ku Japan.

出版信息

Clin Case Rep. 2020 Nov 11;9(1):278-281. doi: 10.1002/ccr3.3514. eCollection 2021 Jan.

DOI:10.1002/ccr3.3514
PMID:33489173
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7813030/
Abstract

Octreotide may be useful in noninsulinoma pancreatogenous hypoglycemia syndrome with nesidioblastosis patients who was on hemodialysis. Continuous octreotide subcutaneous infusion can reduce side-effects and stabilize plasma glucose levels.

摘要

奥曲肽可能对患有胰岛细胞增殖症的非胰岛素瘤胰腺源性低血糖综合征且正在接受血液透析的患者有用。持续皮下输注奥曲肽可减少副作用并稳定血糖水平。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/23d7/7813030/afb2028f4c3f/CCR3-9-278-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/23d7/7813030/47aabe79a9f6/CCR3-9-278-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/23d7/7813030/46e19222be27/CCR3-9-278-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/23d7/7813030/afb2028f4c3f/CCR3-9-278-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/23d7/7813030/47aabe79a9f6/CCR3-9-278-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/23d7/7813030/46e19222be27/CCR3-9-278-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/23d7/7813030/afb2028f4c3f/CCR3-9-278-g003.jpg

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本文引用的文献

1
Clinical practice guidelines for congenital hyperinsulinism.先天性高胰岛素血症临床实践指南。
Clin Pediatr Endocrinol. 2017;26(3):127-152. doi: 10.1297/cpe.26.127. Epub 2017 Jul 27.
2
Selective Arterial Calcium Stimulation With Hepatic Venous Sampling Differentiates Insulinoma From Nesidioblastosis.选择性动脉钙刺激试验联合肝静脉采血可鉴别胰岛素瘤与胰岛细胞增殖症。
J Clin Endocrinol Metab. 2015 Nov;100(11):4189-97. doi: 10.1210/jc.2015-2404. Epub 2015 Aug 27.
3
Insulinoma in a patient with chronic renal failure due to type 2 diabetes mellitus treated effectively with diazoxide.
在基层医疗环境中运用转化科学及持续葡萄糖监测来管理胰岛细胞增殖症：一例病例报告及文献综述
Cureus. 2024 Apr 30;16(4):e59388. doi: 10.7759/cureus.59388. eCollection 2024 Apr.
4
Diffuse, Adult-Onset Nesidioblastosis/Non-Insulinoma Pancreatogenous Hypoglycemia Syndrome (NIPHS): Review of the Literature of a Rare Cause of Hyperinsulinemic Hypoglycemia.弥漫性成人起病的胰岛细胞增殖症/非胰岛素瘤性胰源性低血糖综合征（NIPHS）：高胰岛素血症性低血糖罕见病因的文献综述
Biomedicines. 2023 Jun 16;11(6):1732. doi: 10.3390/biomedicines11061732.
5
Adult focal β-cell nesidioblastosis: A case report.成人局灶性胰岛细胞增殖症：一例报告。
World J Clin Cases. 2023 Jan 6;11(1):150-156. doi: 10.12998/wjcc.v11.i1.150.
一名因2型糖尿病导致慢性肾衰竭的患者患胰岛素瘤，用二氮嗪治疗有效。
Intern Med. 2015;54(6):621-5. doi: 10.2169/internalmedicine.54.3621. Epub 2015 Jan 15.
4
Nesidioblastosis in adults.成人胰岛细胞瘤。
Neoplasma. 2014;61(3):252-6. doi: 10.4149/neo_2014_047.
5
Efficacy and safety of long-term, continuous subcutaneous octreotide infusion for patients with different subtypes of KATP-channel hyperinsulinism.长期持续皮下奥曲肽输注治疗不同亚型 KATP 通道活性过高胰岛素血症患者的疗效和安全性。
Clin Endocrinol (Oxf). 2013 Jun;78(6):891-7. doi: 10.1111/cen.12075. Epub 2013 Apr 6.
6
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Endocr J. 2006 Feb;53(1):95-100. doi: 10.1507/endocrj.53.95.
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A case of hyperinsulinemia of undetermined origin, successfully treated with long-acting octreotide.一例病因不明的高胰岛素血症患者，经长效奥曲肽治疗成功。
Endocr J. 2005 Oct;52(5):511-7. doi: 10.1507/endocrj.52.511.
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Management of hyperinsulinemia with diazoxide in an elderly hemodialysis patient.老年血液透析患者使用二氮嗪治疗高胰岛素血症
Nephron. 2001 Nov;89(3):337-9. doi: 10.1159/000046095.