Petrou Petros, Chalkiadaki Evangelia, Errera Marie-Helene, Liyanage Sidath, Wickham Louisa, Papakonstantinou Evangelia, Karamaounas Aristotelis, Kanakis Menelaos, Georgalas Ilias, Kandarakis Stylianos, Charteris David
First Ophthalmology Department, "G. Gennimatas" Hospital, National and Kapodistrian University of Athens, Athens, Greece.
University of Pittsburg, Pittsburgh, PA, USA.
J Ophthalmol. 2020 Dec 21;2020:9457670. doi: 10.1155/2020/9457670. eCollection 2020.
To analyze the optical coherence tomography (OCT) characteristics as well as the clinical and demographic features to investigate their possible role to the course of vitreomacular traction syndrome.
The inclusion criteria were vitreomacular adhesion with traction causing distortion of the retinal architecture, with or without the presence of an epiretinal membrane, regardless of the size of the adhesion; age >18 years; follow-up of at least three months; and adequate quality OCT scan. Measurements of foveal thickness, average macular thickness, macular volume, maximum vertical and horizontal vitreomacular adhesion, nasal and temporal angles of traction, hyaloid hyperreflectivity, the presence of an epiretinal membrane (ERM), and cone outer segment tips detachment were obtained.
150 eyes were included in the analysis. 36 eyes (24%) developed complete resolution at the last visit, 19 eyes (12.7%) formed a full-thickness macular hole, and 95 eyes (63.3%) showed no resolution of the traction. Better BCVA at the first visit was associated with an increased likelihood of resolution of the VMT, but increasing age, CMT, and BCVA in the end of the follow-up was associated with a reduction in the likelihood of resolving. Of the other variables that were studied, no statistical significant predictors were identified.
Better BCVA in the first visit was associated with an increased likelihood of resolution of the VMT that occurred in 24% of our cases. Other factors such as the vertical area of adhesion and the angle of adhesion were not identified as prognostic factors affecting the clinical course of the disease.
分析光学相干断层扫描(OCT)特征以及临床和人口统计学特征,以研究它们在玻璃体黄斑牵引综合征病程中可能发挥的作用。
纳入标准为存在玻璃体黄斑粘连并伴有牵引导致视网膜结构扭曲,无论有无视网膜前膜,粘连大小不限;年龄>18岁;随访至少三个月;以及OCT扫描质量合格。测量了黄斑中心凹厚度、平均黄斑厚度、黄斑体积、最大垂直和水平玻璃体黄斑粘连、牵引的鼻侧和颞侧角度、玻璃体后界膜高反射性、视网膜前膜(ERM)的存在以及视锥细胞外段顶端脱离情况。
150只眼纳入分析。36只眼(24%)在最后一次随访时完全缓解,19只眼(12.7%)形成了全层黄斑裂孔,95只眼(63.3%)牵引未缓解。首次就诊时较好的最佳矫正视力(BCVA)与玻璃体黄斑牵引(VMT)缓解的可能性增加相关,但随访末期年龄增加、中心凹厚度(CMT)增加和BCVA降低与缓解可能性降低相关。在研究的其他变量中,未发现有统计学意义的预测因素。
首次就诊时较好的BCVA与VMT缓解的可能性增加相关,VMT缓解在我们的病例中占24%。其他因素如粘连的垂直面积和粘连角度未被确定为影响疾病临床病程的预后因素。