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一例寻常型天疱疮患者的卡波西水痘样疹:病例报告及文献复习

Kaposi Varicelliform Eruption in a Patient with Pemphigus Vulgaris: A Case Report and Review of the Literature.

作者信息

Baaniya Bibisha, Agrawal Sudha

机构信息

Department of Dermatology and Venerology, B.P. Koirala Institute of Health Sciences, Dharan, Nepal.

出版信息

Case Rep Dermatol Med. 2020 Dec 30;2020:6695342. doi: 10.1155/2020/6695342. eCollection 2020.

DOI:10.1155/2020/6695342
PMID:33489386
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7790587/
Abstract

Haemorrhagic crusted lesions over pre-existing pemphigus vulgaris erosions should arouse suspicion of Kaposi varicelliform eruption (KVE). Immediate treatment with antivirals helps to prevent mortality and morbidities. Here, we report a case of a 67-year-old male who developed haemorrhagic crusted lesions on pre-existing pemphigus lesions during his hospital stay and obtained almost 90% resolution of cutaneous lesions of Pemphigus vulgaris as well as Kaposi varicelliform eruption within 2 weeks of acyclovir treatment along with the continuation of systemic steroids. We also highlight the review of the literature of other reported cases with its management.

摘要

在既往寻常型天疱疮糜烂基础上出现的出血性结痂性皮损应怀疑为水痘样疹(KVE)。立即使用抗病毒药物治疗有助于预防死亡和并发症。在此,我们报告一例67岁男性病例,该患者在住院期间,在既往天疱疮皮损上出现了出血性结痂性皮损,在接受阿昔洛韦治疗并继续使用全身性激素的2周内,寻常型天疱疮以及水痘样疹的皮肤损害几乎消退了90%。我们还着重回顾了其他已报道病例的文献及其治疗方法。

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本文引用的文献

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Loss of ATP2A2 Allows Herpes Simplex Virus 1 Infection of a Human Epidermis Model by Disrupting Innate Immunity and Barrier Function.ATP2A2 的缺失通过破坏先天免疫和屏障功能允许单纯疱疹病毒 1 感染人类表皮模型。
J Invest Dermatol. 2018 Dec;138(12):2540-2549. doi: 10.1016/j.jid.2018.05.019. Epub 2018 Jun 2.
2
Kaposi varicelliform eruption.卡波西水痘样疹
Indian Dermatol Online J. 2015 Sep-Oct;6(5):364-6. doi: 10.4103/2229-5178.164484.
3
Kaposi varicelliform eruption in patients with autoimmune bullous dermatoses.自身免疫性大疱性皮肤病患者的卡波西水痘样疹
Int J Dermatol. 2016 Mar;55(3):e136-40. doi: 10.1111/ijd.13091. Epub 2015 Oct 24.
4
Severe multi-resistant pemphigus vulgaris: prolonged remission with a single cycle of rituximab.重症多重耐药寻常型天疱疮:利妥昔单抗单周期治疗实现长期缓解
An Bras Dermatol. 2013 Jul-Aug;88(4):639-42. doi: 10.1590/abd1806-4841.20131990.
5
A case series of kaposi's varicelliform eruption in dermatology in-patients in a tertiary care centre.
Indian J Dermatol. 2011 Jan;56(1):110-5. doi: 10.4103/0019-5154.77572.
6
Pitfall: pemphigus herpeticatus should not be confounded with resistant pemphigus vulgaris.误区:疱疹样天疱疮不应与耐药性寻常型天疱疮相混淆。
J Dermatolog Treat. 2010 Sep;21(5):311-3. doi: 10.3109/09546630903287452.
7
Human immunodeficiency virus and pemphigus vulgaris: an interesting association.人类免疫缺陷病毒与寻常型天疱疮:一种有趣的关联。
Indian J Dermatol Venereol Leprol. 2007 Sep-Oct;73(5):354-5. doi: 10.4103/0378-6323.35745.
8
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9
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