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抗肾小球基底膜病作为新型冠状病毒肺炎的潜在并发症:一例病例报告及文献综述

Anti-Glomerular Basement Membrane Disease as a Potential Complication of COVID-19: A Case Report and Review of Literature.

作者信息

Nahhal Sarah, Halawi Ahmad, Basma Hadil, Jibai Ali, Ajami Zeinab

机构信息

Internal Medicine, Lebanese University Faculty of Medicine, Beirut, LBN.

Nephrology, Bahman Hospital, Beirut, LBN.

出版信息

Cureus. 2020 Dec 15;12(12):e12089. doi: 10.7759/cureus.12089.

Abstract

Since the COVID-19 outbreak has started, many reports showed that COVID-19 does not affect only the respiratory system but can alter multiple organs including kidneys. Anti-glomerular basement membrane disease (anti-GBM) is a systemic disease affecting mainly kidneys and lungs. It can sometimes be triggered by a respiratory infection such as influenza however the mechanism is not clear yet. We describe a novel case of Anti-GBM disease possibly complicating COVID-19. We report a case of a 63-year-old man who was admitted to our hospital for fever and myalgia and was found to have COVID-19. During hospitalization, he developed kidney injury along with pulmonary hemorrhage and was found to have anti-GBM antibodies. Our patient was treated as a case of Anti-GBM disease potentially triggered by COVID-19. Hence, the anti-GBM disease could be a potential complication of COVID-19.

摘要

自新冠疫情爆发以来,许多报告显示,新冠病毒不仅会影响呼吸系统,还会改变包括肾脏在内的多个器官。抗肾小球基底膜病(anti-GBM)是一种主要影响肾脏和肺部的全身性疾病。它有时可能由流感等呼吸道感染引发,但其机制尚不清楚。我们描述了一例可能并发新冠病毒感染的新型抗GBM病病例。我们报告了一名63岁男性患者,因发热和肌痛入院,被诊断为感染了新冠病毒。住院期间,他出现了肾损伤并伴有肺出血,且检测出抗GBM抗体。我们的患者被作为可能由新冠病毒引发的抗GBM病病例进行治疗。因此,抗GBM病可能是新冠病毒感染的一种潜在并发症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b70e/7805497/cdf2496c0f7f/cureus-0012-00000012089-i01.jpg

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