Noyola Estela, Noor Asif, Sweeney Nicole, Chan Joshua, Ramesh Rahul, Calixte Rose, Krilov Leonard R
Department of Pediatrics, NYU Long Island School of Medicine, Mineola, NY, United States.
Department of Community Health and Social Medicine, The City University of New York (CUNY) School of Medicine, New York, NY, United States.
Front Pediatr. 2020 Dec 29;8:576676. doi: 10.3389/fped.2020.576676. eCollection 2020.
The aim of this study was to examine the prevalence of bandemia in confirmed respiratory viral infections in febrile infants and children presenting to the emergency department. An observational retrospective study from January 1, 2016, through December 31, 2016, was conducted in patients between the ages of ≥ 1 month and ≤ 5 years presenting to the emergency room with fever and who had a complete blood cell count performed. Patients were separated into seven groups based on the type of respiratory viral infection. Inclusion criteria strictly counted children with viral infections and absence of clinical and laboratory evidence of a bacterial coinfection. A total of 419 patients had a documented viral infection. A significant proportion of these children were found to have bandemia; children with adenovirus (17%), respiratory syncytial virus (RSV) (14.9%), human metapneumovirus (hMPV) (13%), and parainfluenza virus (7.9%) had the highest prevalence when the cutoff for bandemia was set at 10%. The prevalence increased to 35.3, 30.9, 40.3, and 15.8% for adenovirus, RSV, hMPV, and parainfluenza virus, respectively, when this cutoff was lowered further to 5%. Band neutrophils are detected frequently in confirmed respiratory viral infections particularly during early stages.
本研究的目的是调查在急诊科就诊的发热婴幼儿和儿童确诊呼吸道病毒感染中杆状核细胞增多症的患病率。对2016年1月1日至2016年12月31日期间年龄在≥1个月至≤5岁之间、因发热到急诊室就诊并进行了全血细胞计数的患者进行了一项观察性回顾性研究。根据呼吸道病毒感染类型将患者分为七组。纳入标准严格限定为患有病毒感染且无细菌合并感染的临床和实验室证据的儿童。共有419例患者记录有病毒感染。发现这些儿童中有很大一部分存在杆状核细胞增多症;当杆状核细胞增多症的临界值设定为10%时,腺病毒感染儿童(17%)、呼吸道合胞病毒(RSV)感染儿童(14.9%)、人偏肺病毒(hMPV)感染儿童(13%)和副流感病毒感染儿童(7.9%)的患病率最高。当该临界值进一步降至5%时,腺病毒、RSV、hMPV和副流感病毒感染儿童的患病率分别升至35.3%、30.9%、40.3%和15.8%。在确诊的呼吸道病毒感染中,尤其是在早期阶段,经常检测到杆状核中性粒细胞。