Balabanov Iu V, Vartanian G A, Silakov V L
Biull Eksp Biol Med. 1988 Feb;105(2):160-3.
It has been experimentally established that special hypophysiotropic factors--precursors of pose asymmetry factors (PAF) are found in the cerebrospinal fluid of donor animals with cortical lesions during the first postoperative hours. These factors, being specific for the location of the cortical lesion in donor animals, appear to be hypophysiotropic peptide substances inducing the production of corresponding PAF by hypophysial cells. The production of certain PAF by the rat hypophysial tissue cultures under the influence of cerebrospinal fluid from cats gives evidence in favour of species nonspecificity of PAF inductors.
实验已证实,在术后最初数小时内,患有皮质损伤的供体动物的脑脊液中发现了特殊的促垂体因子——姿势不对称因子(PAF)的前体。这些因子对供体动物皮质损伤的位置具有特异性,似乎是诱导垂体细胞产生相应PAF的促垂体肽物质。大鼠垂体组织培养物在猫脑脊液的影响下产生某些PAF,这证明了PAF诱导剂的种属非特异性。