Milokhin A A, Iakushova A M
Biull Eksp Biol Med. 1988 Mar;105(3):357-9.
Synaptogenesis in presumptive cerebral cortex was studied in 7-8 week human embryos by electron microscopy. The first synapses in the regions studied appeared in 7-week embryos. These synapses were detected only in the marginal zone of the developing human cerebral cortex, where they were localized on the somas and processes of the young Cajal-Retzius' neurons. A functional role of early embryonic synaptogenesis in the developing human cerebral cortex is suggested.
通过电子显微镜研究了7-8周龄人类胚胎中假定大脑皮质的突触发生。在所研究的区域中，最早的突触出现在7周龄的胚胎中。这些突触仅在发育中的人类大脑皮质的边缘区被检测到，它们位于年轻的Cajal-Retzius神经元的胞体和突起上。提示早期胚胎突触发生在发育中的人类大脑皮质中具有功能作用。
