Covey T R, Silvestre D, Hoffman M K, Henion J D
Equine Drug Testing and Toxicology, New York State College of Veterinary Medicine, Cornell University, Ithaca 14850.
Biomed Environ Mass Spectrom. 1988 Jan 1;15(1):45-56. doi: 10.1002/bms.1200150107.
A method is described for the screening, quantification and confirmation of a variety of estronenic substances in animal tissues. A solid-phase extraction technique combined with a liquid/liquid extraction allows for rapid sample preparation and high throughput for the following compounds in bovine liver, muscle and kidney: diethylstilbestrol, dienestrol, hexestrol, zeranol, taleranol, zearalanone, zearalenone, zearalenol, estradiol and estriol. Gas chromatography/mass spectrometry and selected ion monitoring is used for the determination with detection limits ranging from 50 to 150 ppt.
描述了一种用于筛选、定量和确证动物组织中多种雌激素类物质的方法。固相萃取技术与液/液萃取相结合，可实现牛肝、肌肉和肾脏中以下化合物的快速样品制备和高通量分析：己烯雌酚、二烯雌酚、己烷雌酚、玉米赤霉醇、他莫昔芬、玉米赤霉酮、玉米赤霉烯酮、玉米赤霉醇、雌二醇和雌三醇。采用气相色谱/质谱联用和选择离子监测进行测定，检测限为50至150 ppt。
