致力于达成散发性前庭神经鞘瘤护理共识:一项改良 Delphi 研究。
Working Toward Consensus on Sporadic Vestibular Schwannoma Care: A Modified Delphi Study.
机构信息
Department of Otolaryngology-Head and Neck Surgery.
Department of Neurologic Surgery, Mayo Clinic, Rochester, Minnesota.
出版信息
Otol Neurotol. 2020 Dec;41(10):e1360-e1371. doi: 10.1097/MAO.0000000000002917.
OBJECTIVE
To address variance in clinical care surrounding sporadic vestibular schwannoma, a modified Delphi study was performed to establish a general framework to approach vestibular schwannoma care. A multidisciplinary panel of experts was established with deliberate representation from key stakeholder societies. External validity of the final statements was assessed through an online survey of registered attendees of the 8th Quadrennial International Conference on Vestibular Schwannoma.
STUDY DESIGN
Modified Delphi method.
METHODS
The panel consisted of 16 vestibular schwannoma experts (8 neurotology and 8 neurosurgery) and included delegates representing the AAOHNSF, AANS/CNS tumor section, ISRS, and NASBS. The modified Delphi method encompassed a four-step process, comprised of one prevoting round to establish a list of focus areas and three subsequent voting rounds to successively refine individual statements and establish levels of consensus. Thresholds for achieving moderate consensus, at ≥67% agreement, and strong consensus, at ≥80% agreement, were determined a priori. All voting was performed anonymously via the Qualtrics online survey tool and full participation from all panel members was required before procession to the next voting round.
RESULTS
Through the Delphi process, 103 items were developed encompassing hearing preservation (N = 49), tumor control and imaging surveillance (N = 20), preferred treatment (N = 24), operative considerations (N = 4), and complications (N = 6). As a result of item refinement, moderate (4%) or strong (96%) consensus was achieved in all 103 final statements. Seventy-nine conference registrants participated in the online survey to assess external validity. Among these survey respondents, moderate (N = 21, 20%) or strong (N = 73, 71%) consensus was achieved in 94 of 103 (91%) statements, and no consensus was reached in 9 (9%). Of the four items with moderate consensus by the expert panel, one had moderate consensus by the conference participants and three had no consensus.
CONCLUSION
This modified Delphi study on sporadic vestibular schwannoma codifies 100% consensus within a multidisciplinary expert panel and is further supported by 91% consensus among an external group of clinicians who regularly provide care for patients with vestibular schwannoma. These final 103 statements address clinically pragmatic items that have direct application to everyday patient care. This document is not intended to define standard of care or drive insurance reimbursement, but rather to provide a general framework to approach vestibular schwannoma care for providers and patients.
目的
针对散发性前庭神经鞘瘤临床护理方面的差异,我们采用改良 Delphi 研究来建立一种通用框架,以处理前庭神经鞘瘤的护理问题。我们成立了一个多学科专家小组,通过精心挑选来自关键利益相关者协会的代表来确保小组的多样性。通过对第八届国际前庭神经鞘瘤会议注册参会者的在线调查,评估最终陈述的外部有效性。
研究设计
改良 Delphi 研究方法。
方法
该小组由 16 名前庭神经鞘瘤专家(8 名神经耳科医生和 8 名神经外科医生)组成,其中包括代表 AAOHNSF、AANS/CNS 肿瘤分会、ISRS 和 NASBS 的代表。改良 Delphi 法包括一个四步流程,包括一轮预投票以确定重点领域清单,以及三轮后续投票以逐步细化各个陈述并确定共识水平。预先确定了达成中度共识(≥67%的一致同意)和高度共识(≥80%的一致同意)的阈值。所有投票均通过 Qualtrics 在线调查工具匿名进行,并且只有在所有小组成员都参与的情况下,才能进入下一轮投票。
结果
通过 Delphi 流程,共制定了 103 项内容,涵盖听力保护(49 项)、肿瘤控制和影像学监测(20 项)、首选治疗(24 项)、手术考虑因素(4 项)和并发症(6 项)。经过项目细化,在所有 103 项最终陈述中均达成中度(4%)或高度(96%)共识。79 名会议注册人员参与了在线调查,以评估外部有效性。在这些调查参与者中,在 103 项陈述中的 94 项(91%)中达成了中度(21 项,20%)或高度(73 项,71%)共识,在 9 项(9%)中未达成共识。在专家小组达成中度共识的四项中,有一项在会议参与者中达成了中度共识,有三项未达成共识。
结论
这项关于散发性前庭神经鞘瘤的改良 Delphi 研究在多学科专家小组中达成了 100%的共识,并得到了经常为前庭神经鞘瘤患者提供护理的外部临床医生小组 91%的共识进一步支持。这些最终的 103 项陈述涉及具有临床实用性的项目,这些项目直接适用于日常患者护理。本文件无意定义护理标准或推动保险报销,而是为提供者和患者提供一个处理前庭神经鞘瘤护理的通用框架。