68Ga- 普乐沙福 PET/CT 高摄取的促肾上腺皮质激素腺瘤。
Cortisol-Producing Adrenal Adenomas With Intense Activity on 68Ga-Pentixafor PET/CT.
机构信息
From the Department of Nuclear Medicine and Beijing Key Laboratory of Molecular Targeted Diagnosis and Therapy in Nuclear Medicine.
Department of Endocrinology and Key Laboratory of Endocrinology, Ministry of Health, and Departments of.
出版信息
Clin Nucl Med. 2021 Apr 1;46(4):350-352. doi: 10.1097/RLU.0000000000003503.
CXC chemokine receptor type 4 as a G-protein-coupled receptor has been confirmed to be highly expressed in functional adrenocortical adenomas. 68Ga-pentixafor, a CXC chemokine receptor type 4-specific ligand, has been reported as a promising tracer to evaluate functional nature of adrenal adenomas. We report intense 68Ga-pentixafor activity of cortisol-producing adrenal adenomas in 2 patients with adrenocorticotropic hormone-independent Cushing syndrome.
CXC 趋化因子受体 4 作为一种 G 蛋白偶联受体，已被证实高度表达于功能性肾上腺皮质腺瘤中。68Ga-五肽昔夫，一种 CXC 趋化因子受体 4 特异性配体，已被报道为评估肾上腺腺瘤功能性质的一种很有前途的示踪剂。我们报告了 2 例促肾上腺皮质激素非依赖性库欣综合征患者中，皮质醇分泌性肾上腺腺瘤有强烈的 68Ga-五肽昔夫活性。
Zotero 插件