Baishya Jiwasmika, Bisht Karishma, Rimbey Jeanette N, Yihunie Kiddist D, Islam Shariful, Al Mahmud Hafij, Waller Jayc E, Wakeman Catherine A
Department of Biological Sciences, Texas Tech University, Lubbock, TX 79409, USA.
Pathogens. 2021 Jan 21;10(2):96. doi: 10.3390/pathogens10020096.
The human microbiota is an array of microorganisms known to interact with the host and other microbes. These interactions can be competitive, as microbes must adapt to host- and microorganism-related stressors, thus producing toxic molecules, or cooperative, whereby microbes survive by maintaining homeostasis with the host and host-associated microbial communities. As a result, these microbial interactions shape host health and can potentially result in disease. In this review, we discuss these varying interactions across microbial species, their positive and negative effects, the therapeutic potential of these interactions, and their implications on our knowledge of human well-being.
人类微生物群是一系列已知与宿主及其他微生物相互作用的微生物。这些相互作用可能是竞争性的，因为微生物必须适应与宿主和微生物相关的应激源，从而产生有毒分子；也可能是合作性的，即微生物通过与宿主及与宿主相关的微生物群落维持内环境稳定而存活。因此，这些微生物相互作用塑造了宿主健康，并可能导致疾病。在本综述中，我们讨论了不同微生物物种间的这些相互作用、它们的正面和负面影响、这些相互作用的治疗潜力以及它们对我们关于人类健康认知的影响。
