Yamaguchi H, Masuda T, Sasaki T, Nojima T
Department of Orthopaedic Surgery, Hokkaido University, School of Medicine, Sapporo, Japan.
Clin Orthop Relat Res. 1988 Apr(229):201-4.
Two cases of previously unreported steroid-induced osteonecrosis of the patella were investigated. The first case was a 46-year-old man who had been receiving steroid therapy for three years for treatment of bronchial asthma. The second was a 32-year-old woman who had been receiving steroid therapy for nine years as treatment of systemic lupus erythematosus. Both reported slight knee pain. The roentgenographic findings revealed increased radiodensity with radiolucency of the upper one-half of the patella. A trephine biopsy revealed focal areas of dead trabecular bone.
对两例此前未报告过的类固醇诱导的髌骨坏死病例进行了调查。第一例是一名46岁男性，因支气管哮喘接受了三年的类固醇治疗。第二例是一名32岁女性，因系统性红斑狼疮接受了九年的类固醇治疗。两人均报告有轻微膝关节疼痛。X线检查结果显示髌骨上半部分的放射密度增加且有透亮区。环钻活检显示有局灶性死骨小梁区域。
