Nowell M A, Grossman R I, Packer R, Hackney D B, Goldberg H I, Bilaniuk L T, Zimmerman R A
Department of Radiology, Hospital of the University of Pennsylvania, Philadelphia 19104.
J Comput Tomogr. 1988 Jan;12(1):61-3. doi: 10.1016/0149-936x(88)90033-1.
A case report of an 11 years old boy with new onset of a seizure disorder is presented. A computed tomography scan demonstrated a noncalcified, nonenhancing focal region of abnormal cortex. A magnetic resonance imaging scan delineated both an isointense area of abnormally thickened gyri and linear areas of abnormal high signal intensity in the subjacent white matter. A review of the radiologic and pathologic literature suggests that this lesion represents the entity focal cortical dysplasia as described by Taylor, et al. This abnormality is part of a spectrum of disorders including hamartomas (of tuberous sclerosis), focal cortical dysplasia and heterotopias.
本文报告一例11岁新发癫痫障碍男孩的病例。计算机断层扫描显示一个非钙化、无强化的皮质异常局灶区域。磁共振成像扫描显示异常增厚脑回的等信号区以及其下方白质内的线状高信号异常区。对放射学和病理学文献的回顾表明，该病变代表了Taylor等人所描述的局灶性皮质发育异常实体。这种异常是一系列疾病的一部分，包括（结节性硬化症的）错构瘤、局灶性皮质发育异常和异位。
