Simons Jorik, Suverein Martje, van Mook Walther, Caliskan Kadir, Soliman Osama, van de Poll Marcel, Delnoij Thijs, Maessen Jos, Mees Barend, Lorusso Roberto
Department of Cardio-Thoracic Surgery, CARIM School for Cardiovascular Diseases, Heart and Vascular Centre, Maastricht University Medical Centre (MUMC+), 6229 HX Maastricht, The Netherlands.
Department of Intensive Care Medicine, Maastricht University Medical Centre (MUMC+), 6229 HX Maastricht, The Netherlands.
J Clin Med. 2021 Jan 20;10(3):383. doi: 10.3390/jcm10030383.
Post-cardiotomy extracorporeal life support (PC-ECLS) has seen a substantial increase in use over the past 10 years. PC-ECLS can be a life-saving procedure and is mostly applied in the presence of unexpected, severe cardio-respiratory complication. Despite PC-ECLS being critical in allowing for organ recovery, it is unfortunately closely connected with an unpredictable outcomes, high morbidity, and, even in the case of cardiac function improvement, potential sustained disabilities that have a life-changing impact for the patient and his or her family. Since the decision to start PC-ECLS is made in an acute setting, there is often only limited or no time for self-determined choices. Due to the major impact of the intervention, it would be highly desirable to obtain informed consent before starting PC-ECLS, since the autonomy of the patient and shared-decision making are two of the most important ethical values in modern medicine. Recent developments regarding awareness of the impacts of a prolonged intensive care stay make this a particularly relevant topic. Therefore, it would be desirable to develop a structural strategy that takes into account the likelihood of such an intervention and the wishes and preferences of the patient, and thus the related autonomy of the patient. This article proposes key points for such a strategy in the form of a PC-ECLS informed consent, a do-(not-)mechanical-circulatory-support order (D(N)MCS), and specific guidelines to determine the extent of the shared decision making. The concept presented in this article could be a starting point for improved and ethical PC-ECLS treatment and application.
在过去10年中,心脏术后体外生命支持(PC-ECLS)的使用量大幅增加。PC-ECLS可能是一种挽救生命的治疗手段,主要用于出现意外的严重心肺并发症的情况。尽管PC-ECLS对于器官恢复至关重要,但不幸的是,它与不可预测的结果、高发病率密切相关,甚至在心脏功能改善的情况下,也可能导致患者及其家人生活发生改变的潜在持续性残疾。由于启动PC-ECLS的决定是在急性情况下做出的,通常只有有限的时间或根本没有时间进行自主选择。鉴于该干预措施的重大影响,在开始PC-ECLS之前获得知情同意非常可取,因为患者的自主权和共同决策是现代医学中两个最重要的伦理价值。最近关于延长重症监护住院时间影响的认识发展使这成为一个特别相关的话题。因此,制定一种结构性策略是可取的,该策略应考虑到这种干预的可能性以及患者的意愿和偏好,从而考虑到患者的相关自主权。本文以PC-ECLS知情同意书、“实施(不实施)机械循环支持医嘱”(D(N)MCS)以及确定共同决策范围的具体指南的形式,提出了这种策略的要点。本文提出的概念可能是改进PC-ECLS治疗及应用并使其符合伦理规范的一个起点。