Macrì Francesco, Angileri Vito, Russo Teresa, Russo Maria Tomiko, Tabbì Marco, Di Pietro Simona
Department of Veterinary Sciences, University of Messina, Viale Palatucci, 98168 Messina, Italy.
Veterinary Practitioner, 91025 Marsala, Italy.
Animals (Basel). 2021 Jan 23;11(2):284. doi: 10.3390/ani11020284.
A 10-month-old mixed-breed male dog was presented with an oblique tibial fracture. The dog was treated with a Robert Jones-like bandage as a conservative approach, and was subjected to X-ray, B-mode, Color Doppler and contrast-enhanced ultrasound (CEUS) examinations during the fracture healing, in order to assess bone hemodynamic changes. B-mode, Power Doppler and CEUS examinations of the fracture gap were performed at 7, 20, 35, and 50 days post-trauma. Quantitative analysis of CEUS and perfusion parameters were obtained. On CEUS, a steep incline in signal numbers was visible in fracture gap at 7 days with peaks at 35 days, after which the vascularization decreases gradually over the next days. In this study, CEUS provided important information on the early stages of the callus formation and on the healing of neighboring tissues, allowing recognition of a correct bone healing. Moreover, the number of vascular signals on CEUS was greater than that on Doppler images on the same day. This report showed the application of CEUS in controlling the fracture healing process. CEUS could be a method of monitoring the remedial processes, assessing the tibial fracture perfusion characterized by low-velocity, small-volume blood flows.
一只10个月大的混种雄性犬因胫骨斜形骨折前来就诊。该犬采用类似罗伯特·琼斯绷带的方式进行保守治疗，并在骨折愈合过程中接受了X线、B超、彩色多普勒和超声造影（CEUS）检查，以评估骨血流动力学变化。在创伤后7天、20天、35天和50天对骨折间隙进行B超、能量多普勒和CEUS检查。获得了CEUS和灌注参数的定量分析结果。在CEUS上，骨折间隙在7天时信号数量呈陡峭上升趋势，在35天时达到峰值，此后血管化在接下来的几天逐渐减少。在本研究中，CEUS提供了关于骨痂形成早期阶段和邻近组织愈合的重要信息，有助于识别正确的骨愈合情况。此外，同一天CEUS上的血管信号数量多于多普勒图像上的。本报告展示了CEUS在控制骨折愈合过程中的应用。CEUS可以作为一种监测治疗过程的方法，评估以低速、小流量血流为特征的胫骨骨折灌注情况。
