Kochhar Anuraj Singh, Sidhu Maninder Singh, Prabhakar Mona, Bhasin Ritasha, Kochhar Gulsheen Kaur, Dadlani Himanshu, Spagnuolo Gianrico, Mehta Viral Vijay
Former Orthodontist, Department of Dentistry, Max Hospital, Gurgaon 122001, India.
Department of Orthodontics, Faculty of Dental Sciences, SGT University, Gurugram 122006, India.
Dent J (Basel). 2021 Jan 22;9(2):14. doi: 10.3390/dj9020014.
The objective of the current study was to evaluate intra- and interobserver bone volume measurements and effect of orientation on the reliability of bone volume evaluation in as-acquired vis-à-vis oriented cone beam computed tomography scans using Osirix software and possible correlation between gender, age, and bone volume required. For this, 31 cone beam computed tomography (CBCT) scans of 14 girls and 17 boys (aged 9-13) with unilateral cleft lip and/or palate who met the inclusion criteria were analyzed. Efficacy and reliability of third party software Osirix for bone volume calculation was assessed using as acquired and oriented volumes by three specialists (a radiologist, an orthodontist, and an oral maxillofacial surgeon). The dataset and readings were anonymized to prevent any bias. Two-way mixed model analysis on as-acquired and oriented observations exhibited intra-class coefficient (ICC) values ≥ 0.90. Wilcoxon signed rank test ( = 0.10) and Kruskal-Wallis ANOVA ( = 0.46) indicated that although a clinical difference in volume assessment was seen between as-acquired and oriented observations (inter-observer and intra-observer), it was statistically insignificant. Spearman's bi-variate correlation analysis revealed a significant relation between the type (side) of cleft and bone volume required to fill the defect ( < 0.05). Although there was clinical difference in bone volume measurement by the three observers, it was insignificant statistically. Clefts on the left side in the patients had significantly more bone required than the right side, whereas age and gender had no relation with bone needed to fill the defect. OsiriX software provided good reliability in measurements of bone volume.
本研究的目的是评估观察者内和观察者间骨体积测量，以及在使用Osirix软件的原始与定向锥束计算机断层扫描中，定向对骨体积评估可靠性的影响，以及性别、年龄与所需骨体积之间可能的相关性。为此，分析了符合纳入标准的14名女孩和17名男孩（年龄9 - 13岁）的31例单侧唇裂和/或腭裂的锥束计算机断层扫描（CBCT）。由三位专家（一名放射科医生、一名正畸医生和一名口腔颌面外科医生）使用原始体积和定向体积评估第三方软件Osirix在计算骨体积方面的有效性和可靠性。数据集和读数进行了匿名处理以防止任何偏差。对原始和定向观察结果进行的双向混合模型分析显示组内相关系数（ICC）值≥0.90。Wilcoxon符号秩检验（ = 0.10）和Kruskal - Wallis方差分析（ = 0.46）表明，尽管在原始和定向观察结果之间（观察者间和观察者内）在体积评估上存在临床差异，但在统计学上不显著。Spearman双变量相关分析显示腭裂类型（侧别）与填充缺损所需的骨体积之间存在显著关系（ < 0.05）。尽管三位观察者在骨体积测量上存在临床差异，但在统计学上不显著。患者左侧的腭裂比右侧需要更多的骨量，而年龄和性别与填充缺损所需的骨量无关。OsiriX软件在骨体积测量方面具有良好的可靠性。
