Broder I, Corey P, Brasher P, Lipa M, Cole P
Gage Research Institute, Department of Medicine, University of Toronto, Ontario, Canada.
Environ Res. 1988 Apr;45(2):179-203. doi: 10.1016/s0013-9351(88)80046-x.
This report describes the second survey of a group of 762 control and urea formaldehyde foam insulated (UFFI) houses performed following an interval of 1 year, after about two-thirds of the UFFI households either had their UFFI removed or performed other UFFI-related remedial work. The UFFI subjects who lived in remedial houses showed a decline in indicators of impaired health status, to roughly equalize with those whose houses were not altered; they continued to show a small excess of adverse health indicators relative to the controls, but at a somewhat lower level than seen in the first survey. This improvement was not associated with changes in indoor levels of formaldehyde. Weak exposure-response relationships were observed between formaldehyde and upper and lower respiratory symptoms, but mainly in the combined UFFI and control populations; these are interpreted as representing the contribution of background levels of formaldehyde to the prevalence of respiratory complaints in the general population. The principal findings of this study were primarily based on subjective variables, but most could be directly validated by objective measurements in the UFFI and control subjects. The support for a causal relationship between impaired health and living in a UFFI house is considered to be moderately strong. However the demonstrated adverse effects are generally minor in nature.
本报告描述了对一组762户对照房屋和脲醛泡沫绝缘(UFFI)房屋进行的第二次调查,此次调查在间隔1年后进行,此时约三分之二的UFFI住户已拆除其UFFI或进行了其他与UFFI相关的补救工作。居住在经过补救房屋中的UFFI受试者健康状况受损指标有所下降,大致与房屋未改动的受试者相当;相对于对照组,他们仍表现出略多的不良健康指标,但水平略低于第一次调查时所见。这种改善与室内甲醛水平的变化无关。在甲醛与上、下呼吸道症状之间观察到微弱的暴露-反应关系,但主要存在于UFFI和对照人群的合并群体中;这些被解释为代表甲醛背景水平对普通人群呼吸道疾病患病率的影响。本研究的主要发现主要基于主观变量,但大多数可通过对UFFI和对照受试者的客观测量直接验证。对健康受损与居住在UFFI房屋之间因果关系的支持被认为中等强度。然而,所显示的不良影响总体上性质轻微。