Paediatrics, Queensland Health, Brisbane, Queensland, Australia
General Paediatrics, Rockhampton Hospital, Rockhampton, Queensland, Australia.
BMJ Case Rep. 2021 Jan 26;14(1):e236037. doi: 10.1136/bcr-2020-236037.
Vertebral osteomyelitis is a rare diagnosis and often delayed diagnosis in children. This is a case of a child presenting with fever, back pain and raised C reactive protein who was found to have a bacteraemia. Initial imaging with CT, MRI of the spine and abdominal ultrasound failed to demonstrate a vertebral osteomyelitis or identify another source of the bacteraemia. Due to the high clinical suspicion of a spinal source of the infection, second-line investigations were arranged. A bone scan identified an area of increase metabolic activity in the 12th thoracic vertebrae (T12) and subsequently a diagnosis was confirmed with a focused MRI of T12. This serves as an opportunity to discuss the diagnostic difficulty presented by paediatric vertebral osteomyelitis and more generally the need for clinicians to pursue their clinical suspicion in the face of false negative results to make an accurate and timely diagnosis.
儿童骨髓炎是一种罕见的诊断,常出现延迟诊断。本病例中,患儿表现为发热、背痛和 C 反应蛋白升高,被发现菌血症。最初的 CT、脊柱 MRI 和腹部超声检查均未发现骨髓炎或其他菌血症源。由于对感染的脊柱源有高度临床怀疑,故安排了二线检查。骨扫描显示第 12 胸椎(T12)有一处代谢活性增加区,随后通过 T12 聚焦 MRI 确诊。本病例提供了一个机会,讨论了儿科骨髓炎带来的诊断困难,更广泛地说,临床医生需要在面对假阴性结果时坚持临床怀疑,以做出准确和及时的诊断。