Ishii H, Suzuki K, Nonaka I
Division of Ultrastructural Research, National Institute of Neuroscience, NCNP, Tokyo, Japan.
Exp Neurol. 1988 Apr;100(1):65-70. doi: 10.1016/0014-4886(88)90201-4.
Internodal Schwann cell fingers were present in the lumbar, cervical, and thoracic spinal roots of adult mice at the age of 3 months, but they were not recognized in five mice examined at the age of 3 weeks. In the L4 ventral roots of ICR mice aged 3 months, the incidence of internodal Schwann cell fingers was 0.79% at the central-peripheral transitional zone and 2.43% at the distal regions, respectively. The ratio of axon diameter to total fiber diameter of myelinated fibers with internodal Schwann cell fingers was lower than that of fibers without them. Therefore, we conclude that internodal Schwann cell fingers are probably related to the developmental increase in the thickness of the myelin sheaths in the ventral spinal roots at all levels of the spinal cord.
3月龄成年小鼠的腰、颈和胸段脊髓神经根中存在节间施万细胞指，但在对3周龄的5只小鼠进行检查时未发现。在3月龄ICR小鼠的L4腹根中，节间施万细胞指在中央-外周过渡区的发生率为0.79%，在远端区域为2.43%。有节间施万细胞指的有髓纤维的轴突直径与总纤维直径之比低于没有节间施万细胞指的纤维。因此，我们得出结论，节间施万细胞指可能与脊髓各节段腹根髓鞘厚度的发育性增加有关。
