Al Mahruqi Ghaitha, Alsabti Hilal, Mukaddirov Mirdavron
Oman Medical Specialty Board, Muscat, Oman.
Cardiothoracic Surgery Division, Department of Surgery, Sultan Qaboos University Hospital, Muscat, Oman.
Eur Heart J Case Rep. 2021 Jan 15;5(1):ytaa559. doi: 10.1093/ehjcr/ytaa559. eCollection 2021 Jan.
Spontaneous coronary artery dissection (SCAD) has emerged as one of the important yet rare causes of acute coronary syndrome that primarily affect young peripartum women without cardiovascular risk factors. Despite the recent improvements in diagnosis and recognition of the importance of SCAD, it remains poorly studied and there has been no consensus of opinion regarding its optimal management.
A 29-year-old breastfeeding woman presented with 1-day history of severe chest pain radiating to the jaw and both shoulders. Cardiovascular examination, 12 leads electrocardiogram, and echocardiography were normal. Troponin levels were elevated; hence, coronary angiogram was done and showed type 2 SCAD of the left anterior descending artery (LAD). The patient was managed conservatively. The next day, she started again to complain of severe chest pain and her troponin levels continued to rise. Repeated coronary angiogram revealed progression of the previous LAD dissection. Another dissection was also noticed in the left circumflex artery. Chest pain recurred over the night and her troponin levels continued to rise. An emergency coronary artery bypass grafting (CABG) was performed. The patient was doing well postoperatively and was discharged home on Day 8.
Our patient presented with acute ischaemic changes secondary to SCAD. The report illustrates the risk factors, pathogenesis, diagnostic work up, and the possible therapeutic options of SCAD, which include conservative management and CABG. The management varies depending on the clinical presentation and the extent of the coronary artery dissection.
自发性冠状动脉夹层(SCAD)已成为急性冠状动脉综合征的重要但罕见的病因之一,主要影响无心血管危险因素的年轻围产期女性。尽管最近在SCAD的诊断和对其重要性的认识方面有所改进,但对其研究仍然不足,关于其最佳治疗方法尚未达成共识。
一名29岁的哺乳期妇女出现胸痛1天,疼痛放射至下颌和双肩。心血管检查、12导联心电图和超声心动图均正常。肌钙蛋白水平升高;因此,进行了冠状动脉造影,显示左前降支动脉(LAD)为2型SCAD。患者接受了保守治疗。第二天,她再次抱怨严重胸痛,肌钙蛋白水平持续升高。重复冠状动脉造影显示先前LAD夹层进展。左回旋支动脉也发现了另一处夹层。夜间胸痛复发,肌钙蛋白水平持续升高。进行了急诊冠状动脉旁路移植术(CABG)。患者术后恢复良好,于第8天出院回家。
我们的患者出现了继发于SCAD的急性缺血性改变。该报告阐述了SCAD的危险因素、发病机制、诊断检查以及可能的治疗选择,其中包括保守治疗和CABG。治疗方法因临床表现和冠状动脉夹层的程度而异。