Serious Mental Illness Treatment Resource and Evaluation Center, U.S. Department of Veterans Affairs, Ann Arbor, Michigan (Szymanski, Hein, McCarthy); Division of Services and Intervention Research, National Institute of Mental Health, Bethesda, Maryland (Schoenbaum); Department of Psychiatry, University of Michigan, Ann Arbor (McCarthy); Office of Mental Health and Suicide Prevention, U.S. Department of Veterans Affairs, Philadelphia (Katz).
Psychiatr Serv. 2021 Apr 1;72(4):408-414. doi: 10.1176/appi.ps.202000282. Epub 2021 Jan 27.
Individuals with mental or substance use disorders have higher mortality rates than people in the general population. How excess mortality varies across health care facilities is unknown. The authors sought to investigate facility-level mortality rates among Veterans Health Administration (VHA) patients who had received diagnoses of mental or substance use disorders.
An electronic medical records-based retrospective cohort study was conducted, encompassing 8,812,373 unique users of 139 VHA facilities from 2011 to 2016. Covariates included age, sex, and past-year diagnoses of serious mental illness, posttraumatic stress disorder, major depressive disorder, other mental health conditions, or substance use disorders. The outcome was all-cause mortality per comprehensive Veterans Affairs/Department of Defense searches of the National Death Index. Proportional hazards regression was used to calculate overall and facility-specific hazard ratios (HRs) for each diagnosis group, adjusted for age, sex, and comorbid medical conditions.
Overall, all-cause mortality was statistically significantly elevated among VHA users with mental health diagnoses (HR=1.21, 95% confidence interval=1.20-1.22). HRs varied across facilities consistently over time. At the VHA facility level, diagnostic groups were significantly correlated with the degree of excess mortality. Results were similar in sensitivity analyses that excluded deaths from suicide or drug or alcohol overdose.
VHA users with mental or substance use disorder diagnoses had elevated mortality rates. Correlation in excess mortality across two periods indicated that facility differences in excess mortality were persistent and therefore potentially associated with facility- and community-level factors, which may help inform quality improvement efforts to reduce mortality rates.
患有精神或物质使用障碍的个体比一般人群的死亡率更高。目前尚不清楚医疗保健机构之间的超额死亡率差异如何。作者试图调查在接受精神或物质使用障碍诊断的退伍军人健康管理局(VHA)患者中,各医疗机构的死亡率。
进行了一项基于电子病历的回顾性队列研究,纳入了 2011 年至 2016 年间 139 个 VHA 设施的 8812373 名独特使用者。协变量包括年龄、性别以及过去一年中严重精神疾病、创伤后应激障碍、重度抑郁障碍、其他心理健康状况或物质使用障碍的诊断。结局是通过对国家死亡索引的全面退伍军人事务/国防部搜索确定的全因死亡率。使用比例风险回归计算每个诊断组的总体和特定设施的危险比(HR),并调整了年龄、性别和合并的医疗条件。
总体而言,VHA 使用者的全因死亡率在精神健康诊断中显著升高(HR=1.21,95%置信区间=1.20-1.22)。随着时间的推移,各设施的 HR 值持续且显著地存在差异。在 VHA 设施层面,诊断组与超额死亡率的程度显著相关。在排除自杀或药物或酒精过量死亡的敏感性分析中,结果相似。
患有精神或物质使用障碍诊断的 VHA 用户死亡率较高。两个时期的超额死亡率的相关性表明,超额死亡率的设施差异是持续存在的,因此可能与设施和社区层面的因素相关,这可能有助于为降低死亡率的质量改进工作提供信息。