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一种新型水灌注式高分辨率测压系统的验证。

VALIDATION OF A NEW WATER-PERFUSED HIGH-RESOLUTION MANOMETRY SYSTEM.

机构信息

Department of Surgery, Federal University of São Paulo, SP, Brazil.

Department of Pathology, UninCor Faculty of Medicine, Vale do Rio Verde University, Belo Horizonte, MG, Brazil.

出版信息

Arq Bras Cir Dig. 2021 Jan 25;33(4):e1557. doi: 10.1590/0102-672020200004e1557. eCollection 2021.

Abstract

BACKGROUND

Water-perfused high resolution manometry system. High-resolution manometry is more costly but clinically superior to conventional manometry. Water-perfused systems may decrease costs, but it is unclear if they are as reliable as solid-state systems, and reference values are interchangeable.

AIM

To validate normal values for a new water-perfusion high-resolution manometry system.

METHODS

Normative values for a 24-sensors water perfused high-resolution manometry system were validated by studying 225 individuals who underwent high resolution manometry for clinical complaints. Patients were divided in four groups: group 1 - gastroesophageal reflux disease; group 2 - achalasia; group 3 - systemic diseases with possible esophageal manifestation; and group 4 - dysphagia.

RESULTS

In group 1, a hypotonic lower esophageal sphincter was found in 49% of individuals with positive 24 h pH monitoring, and in 28% in pH-negative individuals. In groups 2 and 3, aperistalsis was found in all individuals. In group 4, only one patient (14%) had normal high-resolution manometry.

CONCLUSIONS

The normal values determined for this low-cost water-perfused HRM system with unique peristaltic pump and helicoidal sensor distribution are discriminatory of most abnormalities of esophageal motility seen in clinical practice.

摘要

背景

水灌注式高分辨率测压系统。高分辨率测压虽然成本更高,但在临床上优于传统测压。水灌注系统可能会降低成本,但目前尚不清楚其是否与固态系统一样可靠,以及参考值是否可互换。

目的

验证一种新型水灌注式高分辨率测压系统的正常值。

方法

通过对 225 名因临床症状而行高分辨率测压的个体进行研究,验证了一种 24 传感器水灌注式高分辨率测压系统的正常值。患者被分为四组:组 1 - 胃食管反流病;组 2 - 贲门失弛缓症;组 3 - 可能有食管表现的系统性疾病;组 4 - 吞咽困难。

结果

在组 1 中,有 49%的 pH 监测阳性的个体存在下食管括约肌低张力,而 pH 阴性的个体中这一比例为 28%。在组 2 和组 3 中,所有个体均存在无蠕动。在组 4 中,仅有 1 名患者(14%)的高分辨率测压正常。

结论

该低成本水灌注式 HRM 系统采用独特的蠕动泵和螺旋传感器分布,其确定的正常值可区分大多数临床实践中所见的食管动力异常。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c8e2/7836072/550f674c1920/0102-6720-abcd-33-04-e1557-gf1a.jpg

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