Instituto Federal de Educação, Ciência e Tecnologia de Goiás, Núcleo de Estudos e Pesquisas em Promoção da Saúde, Goiânia, GO, Brasil.
Universidade Federal de Goiás, Instituto de Patologia Tropical e Saúde Pública, Goiânia, GO, Brasil.
Epidemiol Serv Saude. 2021 Jan 22;30(1):e2019371. doi: 10.1590/S1679-49742021000100002. eCollection 2021.
To analyze temporal trend and spatial distribution of syphilis in pregnancy and congenital syphilis in Goiás State, Brazil, between 2007 and 2017.
This was an ecological time series and spatial distribution study with data obtained from the Notifiable Health Conditions Information System. Prais-Winsten Regression was used to analyze indicator trends by health macro-region. Descriptive spatial analysis was performed to verify case distribution in three different years in the period.
Between 2007 and 2017, 7,679 cases of syphilis in pregnancy and 1,554 congenital syphilis cases were reported. A rising trend was found in the rates of syphilis in pregnancy (annual percent change [APC] = 18.0 - 95% confidence interval [95%CI] 15.3;20.8) as well as in congenital syphilis rates (APC=16.8 - 95%CI 20.1;33.8); and a 326% increase in the number of municipalities with a congenital syphilis incidence rate >0.5/1,000 live births.
Growth in syphilis in pregnancy and congenital syphilis detection rates was identified, as was growth in the number of municipalities reporting cases.
分析 2007 年至 2017 年巴西戈亚斯州妊娠梅毒和先天性梅毒的时间趋势和空间分布。
本研究为生态时间序列和空间分布研究，数据来自法定传染病信息系统。采用普赖斯-温斯坦回归分析按卫生大区划分的指标趋势。在该期间的三个不同年份进行描述性空间分析，以验证病例的分布情况。
2007 年至 2017 年期间，共报告了 7679 例妊娠梅毒和 1554 例先天性梅毒病例。妊娠梅毒的发病率呈上升趋势（年变化百分比 [APC]=18.0-95%置信区间[95%CI]15.3-20.8），先天性梅毒的发病率也呈上升趋势（APC=16.8-95%CI 20.1-33.8）；先天性梅毒发病率超过 0.5/1000 活产儿的市数量增加了 326%。
妊娠梅毒和先天性梅毒的检出率呈上升趋势，报告病例的市数量也呈上升趋势。
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