NOVA Faculdade, Curso de Enfermagem, Contagem, MG, Brasil.
Universidade Federal de Minas Gerais, Departamento de Enfermagem Materno-Infantil e Saúde Pública, Belo Horizonte, MG, Brasil.
Epidemiol Serv Saude. 2021 Oct 8;30(4):e2021128. doi: 10.1590/S1679-49742021000400006. eCollection 2021.
To analyze the trend of notifications of gestational and congenital syphilis in Minas Gerais, Brazil, from 2009 to 2019.
This was an ecological time series study which took the state of Minas Gerais as its unit of analysis, based on data reported on the Notifiable Health Conditions Information System (SINAN). The Prais-Winsten autoregressive model was used to verify trends.
20,348 cases of gestational syphilis and 11,173 cases of congenital syphilis were reported. Average percentage annual increase was 36.7% (95%CI 32.5;41.0), for gestational syphilis incidence rates, and 32.8% (95%CI 28.0;37.8) for congenital syphilis incidence rates (p<0.001).
The temporal trend analysis showed that gestational and congenital syphilis incidence rates had significant increasing trends, which may be related to inadequate treatment or failure to treat syphilis during pregnancy.
分析巴西米纳斯吉拉斯州 2009 年至 2019 年期间妊娠和先天性梅毒报告病例的趋势。
本研究采用生态时间序列分析，以米纳斯吉拉斯州为分析单位，基于传染病报告信息系统（SINAN）报告的数据。采用普赖斯-温斯坦自回归模型来验证趋势。
共报告了 20348 例妊娠梅毒和 11173 例先天性梅毒病例。妊娠梅毒发病率的年均增长率为 36.7%（95%CI 32.5；41.0），先天性梅毒发病率的年均增长率为 32.8%（95%CI 28.0；37.8）（p<0.001）。
时间趋势分析显示，妊娠和先天性梅毒的发病率呈显著上升趋势，这可能与怀孕期间梅毒治疗不充分或治疗失败有关。
