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越南胡志明市美沙酮维持治疗患者中苯丙胺类兴奋剂使用情况及相关因素的横断面研究。

Prevalence of Amphetamine-Type Stimulant Use and Related Factors among Methadone Maintenance Patients in Ho Chi Minh City Vietnam: A Cross-Sectional Study.

机构信息

Department of Disease Control and Prevention, Pasteur Institute of Ho Chi Minh City, Ho Chi Minh City, Vietnam.

Center for Population Health Science, Hanoi University of Public Health, Hanoi, Vietnam.

出版信息

J Psychoactive Drugs. 2021 Sep-Oct;53(4):355-363. doi: 10.1080/02791072.2020.1871126. Epub 2021 Jan 27.

Abstract

The objective of this study was to determine the prevalence of amphetamine-type stimulant use and associated factors among methadone maintenance treatment (MMT) patients. In 2018, a cross-sectional study was conducted on 967 MMT patients at two methadone clinics in Ho Chi Minh City that serve Vietnamese patients. Amphetamine-type stimulant use was assessed by rapid urine test and face-to-face interview using the Alcohol, Smoking, Substance Involvement Screening Test (ASSIST) tool. The prevalence of amphetamine-type stimulant use assessed by urine test was 25.4%. According to ASSIST, the prevalence of moderate and high risk amphetamine-type stimulant use was 15.5% and 1.1%, respectively. Amphetamine-type stimulant use and hazardous use were more prevalent in younger patients, having a part-time job, drug injection, having a lower score of self-health assessment, treated with a higher dose of methadone and missing methadone dose in the past 3 months. By contrast, patients who were HIV positive were less likely to use amphetamine-type stimulants. Cannabis and heroin use were significantly associated with amphetamine-type stimulant use (OR = 1.46; 95% CI: 1.38-8.67; and OR = 1.50; CI: 1.04-2.18, respectively) and hazardous use (OR = 4.07; CI: 1.67-9.92; and OR = 2.38; CI: 1.56-3.63, respectively). Screening and interventions are needed to cope with this issue on time, particularly in young patients, having drug injection and concurrent drugs user groups.

摘要

本研究旨在确定美沙酮维持治疗(MMT)患者中苯丙胺类兴奋剂的使用情况及其相关因素。2018 年,在胡志明市的两家美沙酮诊所对 967 名美沙酮维持治疗患者进行了横断面研究,这些患者均为越南人。使用尿液检测和酒精、吸烟、物质使用情况筛查测试(ASSIST)工具进行面对面访谈来评估苯丙胺类兴奋剂的使用情况。尿液检测评估的苯丙胺类兴奋剂使用率为 25.4%。根据 ASSIST,中、高度风险苯丙胺类兴奋剂使用率分别为 15.5%和 1.1%。年轻患者、兼职、药物注射、自我健康评估得分较低、接受较高剂量美沙酮治疗和过去 3 个月漏服美沙酮的患者中,苯丙胺类兴奋剂的使用率和危险使用率更高。相比之下,HIV 阳性患者使用苯丙胺类兴奋剂的可能性较小。大麻和海洛因的使用与苯丙胺类兴奋剂的使用(比值比 [OR] = 1.46;95%置信区间 [CI]:1.38-8.67;和 OR = 1.50;CI:1.04-2.18)和危险使用(OR = 4.07;CI:1.67-9.92;和 OR = 2.38;CI:1.56-3.63)显著相关。需要进行筛查和干预,以便及时应对这一问题,特别是在年轻患者、有药物注射和同时使用其他药物的群体中。

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