Asahara Yuki, Mukai Taiji, Suda Machiko, Suzuki Masahiko
Department of Neurology, the Jikei University Katsushika Medical Center.
Rinsho Shinkeigaku. 2021 Feb 23;61(2):140-143. doi: 10.5692/clinicalneurol.cn-001517. Epub 2021 Jan 26.
Anosmia is a frequently experienced symptom in coronavirus disease 2019 (COVID-19). Previous studies have suggested the potential use of olfactometry to identify infected individuals. We performed a sequential olfactometry using the odor stick identification test for Japanese (OSIT-J) in a COVID-19 patient without pneumonia. The test uses 12 odorants that are familiar to the Japanese population. Our patient was a 56-year-old man diagnosed with COVID-19 who was admitted to our hospital following the development of anosmia. He had no respiratory symptoms except pharyngeal pain. Chest CT findings did not reveal the presence of pneumonia. The patient underwent OSIT-J on the 1st hospital day, and his score was 1 out of 12. Following the olfactometry, ciclesonide was administered. The patient did not develop any new symptoms during hospitalization, and his anosmia was gradually improved. The OSIT-J scores were 9 and 11 on the 7th and 16th hospital day, respectively. The patient was discharged on the 25th hospital day after two negative PCR test results. In our case, OSIT-J could identify anosmia in a COVID-19 patient. Some COVID-19 patients are asymptomatic, expect for olfactory disturbances, and OSIT-J may help identify such patients in the Japanese population.
嗅觉丧失是2019冠状病毒病(COVID-19)中经常出现的症状。先前的研究表明嗅觉测量法可用于识别感染者。我们对一名无肺炎的COVID-19患者使用日本嗅觉棒识别测试(OSIT-J)进行了连续嗅觉测量。该测试使用12种日本人群熟悉的气味剂。我们的患者是一名56岁男性,被诊断为COVID-19,在出现嗅觉丧失后入院。除咽痛外,他没有呼吸道症状。胸部CT检查结果未显示有肺炎。患者在入院第1天接受了OSIT-J测试,其得分为12分中的1分。嗅觉测量后,给予环索奈德治疗。患者在住院期间未出现任何新症状,其嗅觉丧失逐渐改善。在住院第7天和第16天,OSIT-J得分分别为9分和11分。在两次PCR检测结果均为阴性后,患者于住院第25天出院。在我们的病例中,OSIT-J能够识别COVID-19患者的嗅觉丧失。一些COVID-19患者除嗅觉障碍外无症状,OSIT-J可能有助于在日本人群中识别此类患者。