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与子宫颈腺癌相关的非细菌性血栓性心内膜炎

Nonbacterial Thrombotic Endocarditis Related to Adenocarcinoma of the Uterine Cervix.

作者信息

Kijpaisalratana Naruchorn, Chutinet Aurauma, Travanichakul Suporn, Kitjawijit Teeraparp, Yokumporn Pajaree, Duangjino Kotchakorn, Suwanwela Nijasri C

机构信息

Division of Neurology, Department of Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.

Chula Neuroscience Center, King Chulalongkorn Memorial Hospital, Bangkok, Thailand.

出版信息

Case Rep Neurol. 2020 Dec 14;12(Suppl 1):183-188. doi: 10.1159/000507277. eCollection 2020 Sep-Dec.

Abstract

We report a 66-year-old female patient who presented with acute onset of visual loss with relative afferent pupillary defect, hemineglect, hemihypesthesia, and apraxia. Magnetic resonance imaging of the brain demonstrated different stages of ischemic stroke in different vascular territories, suggesting cardiogenic embolism. Past history was significant for advanced-stage adenocarcinoma of the uterine cervix under chemoradiation treatment. On echocardiogram, vegetation at the aortic valve was observed. With the absence of evidence of infectious endocarditis, diagnosis of nonbacterial thrombotic endocarditis was made, and the patient was treated by long-term anticoagulant. This case is unique in terms of the adenocarcinoma cell type of cervical cancer, which is uncommon and has been rarely reported to be related to nonbacterial thrombotic endocarditis.

摘要

我们报告了一名66岁女性患者,她出现急性视力丧失,并伴有相对传入性瞳孔障碍、偏侧忽视、偏身感觉减退和失用症。脑部磁共振成像显示不同血管区域存在不同阶段的缺血性中风,提示心源性栓塞。既往史显示患者曾接受放化疗,患有晚期子宫颈腺癌。超声心动图显示主动脉瓣有赘生物。由于缺乏感染性心内膜炎的证据,诊断为非细菌性血栓性心内膜炎,患者接受了长期抗凝治疗。该病例在子宫颈癌的腺癌细胞类型方面具有独特性,这种类型并不常见,很少有报道称其与非细菌性血栓性心内膜炎有关。

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