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睾丸肿瘤的保守性实质手术

Conservative parenchymal surgery in testicular tumors.

作者信息

Ibarra Rodríguez M R, Murcia Pascual F J, Vázquez Rueda F, de Lucio Rodríguez M, Siu Uribe A, Ramnarine Sánchez S D, Escassi Gil A, Paredes Esteban R M

机构信息

Pediatric Surgery Clinical Management Unit. Reina Sofía University Hospital. Córdoba (Spain).

Pediatric Surgery Clinical Management Unit. Reina Sofía University Hospital. Córdoba (Spain). Professor at the Faculty of Medicine. University of Cordoba. Maimónides Institute for Biomedical Research of Córdoba (IMIBIC).

出版信息

Cir Pediatr. 2021 Jan 1;34(1):15-19.

Abstract

OBJECTIVES

Orchiectomy is the most widely used surgical technique in testicular tumors (TT). However, according to tumor size, tumor markers, and histology, tumorectomy can be considered as the technique of choice, since these tumors are mostly benign. We present our experience with conservative surgery.

MATERIAL AND METHODS

A retrospective study of 21 TT cases in 19 patients under 14 years of age treated in our healthcare facility from 1998 to 2018 was carried out. The following variables were analyzed: age, laterality, histological type, evolution, presence or absence of recurrence, and ultrasound and analytical follow-up. The therapeutic attitude used was reviewed while assessing the possibility of testicular preservation in selected patients.

RESULTS

Conservative surgery was performed in 9 TT cases in 7 patients (2 bilateral cases). Mean age was 6 years (0-13 years). 86% of cases started as an asymptomatic scrotal mass. No significant differences were found in terms of laterality. Tumor markers were negative before and after surgery, except in an infant with high alpha-fetoprotein, which was normalized in the postoperative period. The histological study diagnosed 7 stromal TTs (three Leydig cell stromal TTs, one bilateral Sertoli cell stromal TT, one hamartoma, and one fibroma) and 2 germ cell TTs (bilateral epidermoid cyst). Evolution was favorable in all cases, without clinical or ultrasound recurrence.

CONCLUSIONS

Conservative surgery of the testicular parenchyma using tumorectomy can be the first therapeutic option in benign tumors and in selected patients with bilateral tumor, since it allows future hormonal and reproductive function to be preserved.

摘要

目的

睾丸切除术是睾丸肿瘤(TT)中应用最广泛的手术技术。然而,根据肿瘤大小、肿瘤标志物和组织学检查,肿瘤切除术可被视为首选技术,因为这些肿瘤大多为良性。我们介绍我们在保守性手术方面的经验。

材料与方法

对1998年至2018年在我们医疗机构接受治疗的19例14岁以下患者的21例TT病例进行了回顾性研究。分析了以下变量:年龄、侧别、组织学类型、病情演变、有无复发以及超声和分析随访情况。在评估选定患者保留睾丸的可能性时,回顾了所采用的治疗方法。

结果

7例患者(2例双侧病例)的9例TT病例实施了保守性手术。平均年龄为6岁(0 - 13岁)。86%的病例最初表现为无症状阴囊肿块。在侧别方面未发现显著差异。除一名甲胎蛋白高的婴儿术后恢复正常外,手术前后肿瘤标志物均为阴性。组织学研究诊断出7例基质性TT(3例Leydig细胞基质性TT、1例双侧支持细胞基质性TT、1例错构瘤和1例纤维瘤)和2例生殖细胞TT(双侧表皮样囊肿)。所有病例病情演变良好,无临床或超声复发。

结论

对于良性肿瘤以及选定的双侧肿瘤患者,采用肿瘤切除术对睾丸实质进行保守性手术可作为首选治疗方法,因为它能够保留未来的激素和生殖功能。

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