Brant A M, Shah S S, Rodgers V G, Hoffmeister J, Herman I M, Kormos R L, Borovetz H S
Department of Surgery, University of Pittsburgh School of Medicine, PA 15261.
J Biomech. 1988;21(2):107-13. doi: 10.1016/0021-9290(88)90004-8.
A perfusion apparatus is employed to reproduce quantifiable pulsatile hemodynamics within freshly excised canine carotid arteries. From measurements of pulsatile intraluminal and transmural pressure and the dynamic radial motion of the vessel wall, calculations are made of the vascular incremental modulus of elasticity and hoop, axial, and radial wall stresses. The results of this investigation suggest that an increase in transmural pressure from 120/80 to 240/120 mmHg produces a marked elevation in incremental modulus and arterial wall stress. These parameters are reduced when transmural pressure is lowered while maintaining intraluminal pressure at physiologic values.
使用一种灌注装置在新鲜切除的犬颈动脉内再现可量化的搏动性血流动力学。通过测量搏动性腔内和跨壁压力以及血管壁的动态径向运动，计算血管的弹性增量模量以及环向、轴向和径向壁应力。本研究结果表明，跨壁压力从120/80 mmHg增加到240/120 mmHg会使弹性增量模量和动脉壁应力显著升高。当跨壁压力降低而腔内压力保持在生理值时，这些参数会降低。
