Department of Physical Therapy for Pediatrics, Faculty of Physical Therapy, Cairo University, Giza, Egypt; Department of Health and Rehabilitation Sciences, College of Applied Medical Sciences, Prince Sattam Bin Abdulaziz University, Al-Kharj, Saudi Arabia.
Department of Physical Therapy for Cardiovascular/Respiratory Disorder and Geriatrics, Faculty of Physical Therapy, Cairo University, Giza, Egypt; Department of Health and Rehabilitation Sciences, College of Applied Medical Sciences, Prince Sattam Bin Abdulaziz University, Al-Kharj, Saudi Arabia.
Complement Ther Med. 2021 Mar;57:102673. doi: 10.1016/j.ctim.2021.102673. Epub 2021 Jan 26.
The purpose of this study was to evaluate the efficacy of transcutaneous electrical nerve stimulation over the acupuncture points (Acu-TENS) on total serum immunoglobulin E (IgE), pulmonary function, and quality of life in adolescents with asthma.
In a double-blind randomized clinical trial, 32 adolescents (age; 12-16 years) with asthma participated and were assigned randomly to receive either the breathing retraining program (control group) or the breathing retraining program plus Acu-TENS application (Acu-TENS group). Acu-TENS was applied for 40 min' day-after-day session for two successive months, with no side-effects reported. Serum IgE, pulmonary function [forced vital capacity (FVC), forced expiratory volume at one second (FEV), and FEV/FVC], and quality of life were evaluated pre- and post-treatment.
Serum IgE (P = 0.028, η = 0.15), Pulmonary function [FVC (P = 0.043, η = 0.13), FEV (P = .046, η = 0.12)], and quality of life (P < .001, η = 0.17) increased significantly in the Acu-TENS group when compared to the control group.
This study demonstrates that the Acu-TENS is an impending asthma treatment that may be used to reinforce the immune system response, ameliorate lung function, and increase the quality of life in adolescents with asthma.
本研究旨在评估经皮神经电刺激穴位（Acu-TENS）对青少年哮喘患者血清总免疫球蛋白 E（IgE）、肺功能和生活质量的疗效。
在一项双盲随机临床试验中，32 名（年龄 12-16 岁）哮喘青少年参与并随机分配接受呼吸训练计划（对照组）或呼吸训练计划加 Acu-TENS 应用（Acu-TENS 组）。Acu-TENS 每天应用 40 分钟，连续两个月，无不良反应报告。治疗前后评估血清 IgE、肺功能[用力肺活量（FVC）、一秒用力呼气量（FEV）和 FEV/FVC]和生活质量。
与对照组相比，Acu-TENS 组血清 IgE（P = 0.028，η = 0.15）、肺功能[FVC（P = 0.043，η = 0.13）、FEV（P = 0.046，η = 0.12）]和生活质量（P < 0.001，η = 0.17）显著增加。
本研究表明，Acu-TENS 是一种有前途的哮喘治疗方法，可用于增强免疫系统反应、改善肺功能和提高哮喘青少年的生活质量。
