Firlit C F, Merkel F K
J Urol. 1977 Oct;118(4):647-50. doi: 10.1016/s0022-5347(17)58138-0.
Our experience with the use of ileal conduits as receptors of renal homografts in 5 of 41 transplant recipients during the preceding 4 years is described. These 5 chronic renal failure patients were between 6 months and 17 years old, and had unsalvageable bladders that required an ileal conduit at an elective time before transplantation. The causes of renal failure in these children included dysplasia and chronic urinary tract infection. In an attempt to retard the rate of renal insufficiency all patients underwent multiple operative procedures on the lower urinary tract. Two cadaveric and 3 kidneys from living relatives were transplanted. One infant (6 months old) died of severe fluid and electrolyte imbalance 5 days post-transplantation. Of the remaining patients 3 are now 2 to 3 1/2 years post-transplantation and exhibit normal homograft function, and 1 died recently of chronic rejection. All conduits functioned well without evidence of ureteroileal obstruction, significant infection or stomal stenosis.
本文描述了我们在过去4年中，对41例移植受者中的5例使用回肠导管作为同种异体肾移植物受体的经验。这5例慢性肾衰竭患者年龄在6个月至17岁之间，膀胱无法挽救，在移植前的择期需要进行回肠导管手术。这些儿童肾衰竭的原因包括发育异常和慢性尿路感染。为了延缓肾功能不全的进展速度，所有患者均接受了多次下尿路手术。移植了2个尸体供肾和3个亲属活体供肾。1例婴儿（6个月大）在移植后5天死于严重的水电解质失衡。其余患者中，3例目前移植后2至3.5年，同种异体移植物功能正常，1例最近死于慢性排斥反应。所有导管功能良好，未出现输尿管回肠梗阻、严重感染或造口狭窄的迹象。
