Zhou Y B
Department of Gastrointestinal Surgery, the Affiliated Hospital of Qingdao University, Qingdao 266003, China.
Zhonghua Wei Chang Wai Ke Za Zhi. 2021 Feb 25;24(2):122-127. doi: 10.3760/cma.j.cn.441530-20200318-00152.
Gastrointestinal cancer and related treatments (surgery and chemoradiotherapy) are associated with declined functional status (FS) that has impact on quality of life, clinical outcome and continuum of care. Psychological distress drives an impressive burden of physiological and psychiatric conditions in oncologic care. Cancer patients often experience anxiety, depression, low self-esteem and fears of recurrence and death. Cancer prehabilitation is a process from cancer diagnosis to the beginning of treatment, which includes psychological, physical and nutritional assessments for a baseline functional level, identification of comorbidity, and targeted interventions that improve patient's health and functional capacity to reduce the incidence and the severity of current and future impairments with cancer, chemoradiotherapy and surgery. Multimodal prehabilitation program encompasses a series of planned, structured, repeatable and purposive interventions including comprehensive physical exercise, nutritional therapy, and relieving anxiety and depression, which integrates into best perioperative management ERAS pathway and aims at using the preoperative period to prevent or attenuate the surgery-related functional decline, to cope with surgical stress and to improve the consequences. However, a number of questions remain in regards to prehabilitation in gastrointestinal cancer surgery, which consists of the optimal makeup of training programs, the timing and approach of the intervention, how to improve compliance, how to measure functional capacity, and how to make cost-effective analysis. Therefore, more high-level evidence-based studies are expected to evaluate the value of implementation of prehabilitation into standard practice.
胃肠道癌症及相关治疗(手术和放化疗)与功能状态(FS)下降有关,这会影响生活质量、临床结局和连续护理。心理困扰在肿瘤护理中带来了令人印象深刻的生理和精神疾病负担。癌症患者常经历焦虑、抑郁、自卑以及对复发和死亡的恐惧。癌症术前康复是一个从癌症诊断到治疗开始的过程,包括对基线功能水平进行心理、身体和营养评估,识别合并症,以及进行有针对性的干预,以改善患者健康和功能能力,降低癌症、放化疗及手术导致的当前和未来损伤的发生率和严重程度。多模式术前康复计划包括一系列有计划、有结构、可重复且有目的的干预措施,包括全面的体育锻炼、营养治疗以及缓解焦虑和抑郁,该计划融入最佳围手术期管理加速康复外科(ERAS)路径,旨在利用术前阶段预防或减轻与手术相关的功能下降,应对手术应激并改善后果。然而,关于胃肠道癌症手术的术前康复仍存在一些问题,包括训练计划的最佳构成、干预的时机和方法、如何提高依从性、如何测量功能能力以及如何进行成本效益分析。因此,期望有更多高水平的循证研究来评估将术前康复纳入标准实践的价值。