1University of Louisville, Schools of Public Health and Medicine, Louisville, Kentucky.
2University of Kentucky, College of Pharmacy, Louisville, Kentucky.
Sr Care Pharm. 2021 Feb 1;36(2):68-82. doi: 10.4140/TCP.n.2021.68.
When selecting and managing psychoactive medications in older people, it is equally important to focus on avoidance of toxicity as it is to focus on efficacy. Higher psychoactive medication load is associated with increased rate and risk of all cause hospitalization. The medication classes used to treat depression and related comorbidities include antidepressants, antipsychotics, stimulants, mood stabilizers, lithium, anxiolytics and sedative hypnotics. This discussion will examine considerations to help avoid medication related problems relevant to medications used to treat depression in the antidepressant pharmacological class.
在为老年人选择和管理精神活性药物时，关注避免毒性与关注疗效同样重要。较高的精神活性药物负荷与所有原因住院率和风险的增加有关。用于治疗抑郁症和相关共病的药物类别包括抗抑郁药、抗精神病药、兴奋剂、心境稳定剂、锂、抗焦虑药和镇静催眠药。本讨论将探讨有助于避免与抗抑郁药药理学类别中用于治疗抑郁症的药物相关的药物相关问题的注意事项。
