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不同止血带压力对全膝关节置换术后疼痛和并发症的影响:一项前瞻性、随机对照试验。

Effect of Different Tourniquet Pressure on Postoperative Pain and Complications After Total Knee Arthroplasty: A Prospective, Randomized Controlled Trial.

机构信息

Department of Orthopaedic Surgery, Thammasat University, Pathum Thani, Bangkok, Thailand.

Department of Orthopaedic Surgery, Chulabhorn International College of Medicine, Thammasat University, Pathum Thani, Bangkok, Thailand.

出版信息

J Arthroplasty. 2021 May;36(5):1638-1644. doi: 10.1016/j.arth.2020.12.049. Epub 2021 Jan 5.

Abstract

BACKGROUND

Tourniquet pressure inflation is commonly selected between 100 and 150 mm Hg above the systolic blood pressure (SBP). Given the lack of evidence to support a given inflation pressure, our study aimed to ascertain the lowest tourniquet pressure that facilitated total knee arthroplasty (TKA) and resulted in the least postoperative pain and complications.

METHODS

In a double-blind, randomized controlled trial of patients scheduled for unilateral primary TKA, 150 were assigned to use tourniquet pressures of SBP + 75 mm Hg (group I), SBP + 100 mm Hg (group II), and SBP + 150 mm Hg (group III). The quality of the bloodless field, total blood loss, and limb swelling were determined perioperatively. Clinical outcomes were evaluated by visual analog scale for pain at thigh and surgical site, serum creatinine phosphokinase levels, wound complications, range of motion, and Knee Society Score.

RESULTS

Visual analog scale for pain at thigh and surgical site were lowest in group I (P < .01) and highest in group III (P < .01). However, the quality of bloodless field at the tibial cutting surface was significantly better in group III compared to group I/II but not at the femoral cutting surface. The total blood loss and limb swelling showed no difference among 3 groups. Postoperative serum creatinine phosphokinase levels at 24 and 48 hours and wound complications in group III were significantly higher than group I (P < .01) and group II (P < .01). Nevertheless, postoperative knee range of motion and Knee Society Score were not significantly different among 3 groups.

CONCLUSION

Post TKA, the lowest tourniquet pressure was associated with significantly less postoperative tourniquet and surgical site pain, muscle damage, and wound complications.

摘要

背景

止血带充气压力通常选择在收缩压(SBP)之上 100 至 150mmHg。鉴于缺乏支持特定充气压力的证据,我们的研究旨在确定可方便进行全膝关节置换术(TKA)且术后疼痛和并发症最少的最低止血带压力。

方法

在一项针对单侧初次 TKA 患者的双盲、随机对照试验中,150 名患者被分配使用 SBP+75mmHg(I 组)、SBP+100mmHg(II 组)和 SBP+150mmHg(III 组)的止血带压力。在围手术期确定无血区域的质量、总失血量和肢体肿胀情况。通过大腿和手术部位疼痛的视觉模拟量表、血清肌酸磷酸激酶水平、伤口并发症、活动范围和膝关节协会评分评估临床结果。

结果

大腿和手术部位疼痛的视觉模拟量表评分在 I 组中最低(P<.01),在 III 组中最高(P<.01)。然而,与 I/II 组相比,III 组在胫骨切割面的无血区域质量显著更好,但在股骨切割面则不然。3 组之间总失血量和肢体肿胀无差异。III 组术后 24 小时和 48 小时的血清肌酸磷酸激酶水平和伤口并发症明显高于 I 组(P<.01)和 II 组(P<.01)。然而,3 组之间术后膝关节活动范围和膝关节协会评分无显著差异。

结论

TKA 后,最低的止血带压力与明显较少的术后止血带和手术部位疼痛、肌肉损伤和伤口并发症相关。

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