Orthopaedics, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, Karnataka, India.
General Medicine, Dr TMA Pai Hospital, Udupi, Melaka-Manipal Medical College, Manipal Academy of Higher Education, Udupi, Karnataka, India.
BMJ Case Rep. 2021 Jan 28;14(1):e238366. doi: 10.1136/bcr-2020-238366.
Synovial sarcomas are deep-seated, genetically distinct, malignant neoplasms seen in young adults, with a male preponderance. They have unusual clinical and pathological presentation and mimic many other sarcomas and carcinomas, making the diagnosis quite challenging. Although four variants are identified, occurrence in the hand is extremely rare and leads to significant morbidity. There is a high incidence of local recurrence and distant metastasis within the first 2 years. We report the case of an elderly woman with monophasic spindle cell synovial sarcoma who presented with painless swelling in her palm and underwent local excision of the neoplasm. At 2-year follow-up, she remains totally asymptomatic with normal function of the hand. We also attempt to give an overview about monophasic spindle cell synovial sarcoma with the differentials, which would help surgeons in prompt diagnosis and appropriate management.
滑膜肉瘤是一种深部、遗传上独特的恶性肿瘤,多见于年轻人,男性居多。它们具有不同寻常的临床表现和病理表现,模仿许多其他肉瘤和癌,使诊断极具挑战性。尽管已经确定了四种变体,但在手部的发生极为罕见,会导致严重的发病率。在头 2 年内,局部复发和远处转移的发生率很高。我们报告了一例老年女性患有单相梭形细胞滑膜肉瘤,她的手掌出现无痛性肿胀,并接受了肿瘤的局部切除。在 2 年的随访中,她完全无症状,手部功能正常。我们还试图概述单相梭形细胞滑膜肉瘤的不同之处,这将有助于外科医生及时诊断和适当治疗。