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手部单相梭形细胞黏液样滑膜肉瘤:边缘切除具有良好的疗效。

Monophasic spindle cell myxoid synovial sarcoma of the hand: promising results with marginal resection.

机构信息

Orthopaedics, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, Karnataka, India.

General Medicine, Dr TMA Pai Hospital, Udupi, Melaka-Manipal Medical College, Manipal Academy of Higher Education, Udupi, Karnataka, India.

出版信息

BMJ Case Rep. 2021 Jan 28;14(1):e238366. doi: 10.1136/bcr-2020-238366.

Abstract

Synovial sarcomas are deep-seated, genetically distinct, malignant neoplasms seen in young adults, with a male preponderance. They have unusual clinical and pathological presentation and mimic many other sarcomas and carcinomas, making the diagnosis quite challenging. Although four variants are identified, occurrence in the hand is extremely rare and leads to significant morbidity. There is a high incidence of local recurrence and distant metastasis within the first 2 years. We report the case of an elderly woman with monophasic spindle cell synovial sarcoma who presented with painless swelling in her palm and underwent local excision of the neoplasm. At 2-year follow-up, she remains totally asymptomatic with normal function of the hand. We also attempt to give an overview about monophasic spindle cell synovial sarcoma with the differentials, which would help surgeons in prompt diagnosis and appropriate management.

摘要

滑膜肉瘤是一种深部、遗传上独特的恶性肿瘤,多见于年轻人,男性居多。它们具有不同寻常的临床表现和病理表现,模仿许多其他肉瘤和癌,使诊断极具挑战性。尽管已经确定了四种变体,但在手部的发生极为罕见,会导致严重的发病率。在头 2 年内,局部复发和远处转移的发生率很高。我们报告了一例老年女性患有单相梭形细胞滑膜肉瘤,她的手掌出现无痛性肿胀,并接受了肿瘤的局部切除。在 2 年的随访中,她完全无症状,手部功能正常。我们还试图概述单相梭形细胞滑膜肉瘤的不同之处,这将有助于外科医生及时诊断和适当治疗。

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本文引用的文献

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Recurrent monophasic synovial sarcoma in a child.一名儿童复发性单相滑膜肉瘤
Indian J Pathol Microbiol. 2019 Oct-Dec;62(4):643-645. doi: 10.4103/IJPM.IJPM_510_18.
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Synovial Sarcoma of Palmar Aspect of Hand and Survival: A Rare Case Report.手掌部滑膜肉瘤与生存情况:1例罕见病例报告
J Clin Diagn Res. 2017 Jul;11(7):XD09-XD11. doi: 10.7860/JCDR/2017/25930.10212. Epub 2017 Jul 1.
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A Tumour in Disguise in the Right Palm- Monophasic Synovial Sarcoma.右手掌的隐匿性肿瘤——单相滑膜肉瘤
J Clin Diagn Res. 2016 May;10(5):ED03-5. doi: 10.7860/JCDR/2016/11112.7748. Epub 2016 May 1.
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Clinical outcomes for patients with synovial sarcoma of the hand.手部滑膜肉瘤患者的临床结局
Springerplus. 2014 Nov 3;3:649. doi: 10.1186/2193-1801-3-649. eCollection 2014.

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