Mishima T, Kobayashi Y, Ohkubo M, Marumo F, Yoshimura H
Jpn Circ J. 1977 Sep;41(9):1009-13. doi: 10.1253/jcj.41.1009.
An adult renal transplant recipient was complicated with cryptococcal lung granuloma and meningitis. Treatment with the antifungal agents, 5-fluorocytocin and clotrimazole had to be discontinued due to side effects. Whereas, the intrathecal administration of amphotericin B proved effective for meningitis but intravenously it induced acute tubular necrosis to the transplanted kidney. In order to cure the persistant fungal lung granulomas in renal transplant patients early surgical excision seems to be essential.
一名成年肾移植受者并发隐球菌性肺肉芽肿和脑膜炎。由于副作用，不得不停止使用抗真菌药物5-氟胞嘧啶和克霉唑。然而，鞘内注射两性霉素B对脑膜炎有效，但静脉注射会导致移植肾发生急性肾小管坏死。为了早期治愈肾移植患者持续存在的真菌性肺肉芽肿，手术切除似乎至关重要。
