Department of General Surgery, Shandong Qianfoshan Hospital, Cheeloo College of Medicine, Shandong University, Jinan, 250014, Shandong, China.
Department of General Surgery, Shandong Provincial Qianfoshan Hospital, the First Hospital Affiliated With Shandong First Medical University, Jinan, China.
Sci Rep. 2021 Jan 28;11(1):2415. doi: 10.1038/s41598-021-82058-x.
Hepatocellular carcinoma (HCC) is one of the most common and most lethal malignant tumors in the world. Microvascular invasion (MVI) is a major risk factor for survival outcomes and intrahepatic metastasis after resection in patients with HCC. Relevant English literatures retrieved using PubMed on the research progress of MVI in patients with HCC were reviewed. For HCC patients, especially those with MVI, it is very important to develop a comprehensive and sequential treatment plan to support the long-term survival of patients. This manuscript reviewed and analyzed the risk factors for MVI; the preoperative prediction of MVI, which informs the selection of surgical strategies; and the current situation and future direction of comprehensive postoperative treatment strategies; to provide a basis for the comprehensive treatment of HCC patients with MVI. For HCC patients with MVI, the preoperative prediction of MVI may play a certain guiding role in planning procedures, and the comprehensive sequential postoperative pathological detection of HCC MVI may provide a basis for treatment decisions.
肝细胞癌（HCC）是世界上最常见和最致命的恶性肿瘤之一。微血管侵犯（MVI）是影响 HCC 患者术后生存结局和肝内转移的主要危险因素。本文复习了使用 PubMed 检索到的关于 HCC 患者 MVI 研究进展的相关英文文献。对于 HCC 患者，尤其是 MVI 患者，制定全面、序贯的治疗方案对支持患者的长期生存非常重要。本文综述并分析了 MVI 的危险因素；术前对 MVI 的预测，这为手术策略的选择提供了信息；以及综合术后治疗策略的现状和未来方向；为 HCC 伴 MVI 患者的综合治疗提供了依据。对于伴有 MVI 的 HCC 患者，术前对 MVI 的预测可能对手术方案的规划起到一定的指导作用，而 HCC 伴 MVI 的综合序贯术后病理检测可能为治疗决策提供依据。
