Kakturskiy L V, Mikhaleva L M, Mishnev O D, Zayratyants O V, Kurilina E V, Komlev A E
Research Institute of Human Morphology, Moscow, Russia.
N.I. Pirogov Russian National Research Medical University of the Ministry of Health of Russia, Moscow, Russia.
Arkh Patol. 2021;83(1):5-11. doi: 10.17116/patol2021830115.
The article presents published and own data about Takotsubo syndrome, a relatively rare heart disease that is similar to acute coronary syndrome, but without significant damage of coronary arteries. The leading pathogenetic factor is the catecholamine-induced stress damage of myocardium with involvement of microvessels. There is a certain underestimation of Takotsubo syndrome by both clinicians and pathologists, so some cases of Takotsubo syndrome are misdiagnosed as acute coronary syndrome. Morphological manifestations of Takotsubo syndrome are characterized by mucoid edema of interstitial myocardial tissue, round-cell infiltration of stroma and focal damage of cardiomyocytes.
本文介绍了关于应激性心肌病的已发表数据及我们自己的数据。应激性心肌病是一种相对罕见的心脏病，类似于急性冠状动脉综合征，但冠状动脉无明显损伤。主要致病因素是儿茶酚胺诱导的心肌应激损伤并累及微血管。临床医生和病理学家对应激性心肌病都存在一定程度的低估，因此一些应激性心肌病病例被误诊为急性冠状动脉综合征。应激性心肌病的形态学表现特征为心肌间质组织的黏液样水肿、基质的圆形细胞浸润以及心肌细胞的局灶性损伤。
