巨大隐球菌假体周围肩部感染：病例报告。
Cryptococcus magnus Periprosthetic Shoulder Infection: A Case Report.
机构信息
Orthopaedic Surgery and Traumatology Department, Hospital de Braga, Braga, Portugal.
Trofa Saúde Group, Porto, Portugal.
出版信息
JBJS Case Connect. 2020 Dec 10;10(4):e20.00507. doi: 10.2106/JBJS.CC.20.00507.
CASE
We present a 68-year-old diabetic man with a periprosthetic shoulder infection (PSI) by Cryptococcus magnus. The fungus was identified 4 weeks after a revision surgery for a chronic bacterial PSI. Treatment was successful with a 2-week course of intravenous liposomal amphotericin B (5 mg/kg) followed by 6 weeks of fluconazole (200 mg/d).
CONCLUSION
To the best of our knowledge, only 2 periprosthetic infections due to Cryptococcus neoformans have been previously reported. This is the first report of cryptococcal involvement of a prosthetic shoulder, and the first identified osteoarticular infection ever by C. magnus.
病例
我们报告了一例 68 岁糖尿病男性患者，其患有新型隐球菌引起的假体肩感染（PSI）。真菌在慢性细菌性 PSI 翻修手术后 4 周被鉴定出来。治疗采用 2 周静脉注射两性霉素 B 脂质体（5 mg/kg），随后 6 周氟康唑（200 mg/d），治疗成功。
结论
据我们所知，之前仅报道过 2 例因新型隐球菌引起的假体感染。这是首例报道的假体肩部新型隐球菌感染，也是首次发现由大隐球菌引起的骨关节炎感染。
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