Imai Y, Abe K, Miura Y, Nihei M, Sasaki S, Minami N, Munakata M, Taira N, Sekino H, Yamakoshi K
Department of Medicine, Tohoku University, Sendai, Japan.
J Hypertens. 1988 Jan;6(1):9-15.
A new portable device for the indirect measurement of arterial blood pressure was successfully applied to detect paroxysmal hypertension and circadian fluctuation of blood pressure in patients with phaeochromocytoma. The device utilizes the volume-oscillometric technique, it is equipped with a microprocessor and allows long-term automatic monitoring of indirect blood pressure in the human finger. Compared with conventional fully automated portable devices of the arm-cuff type, our current equipment is lighter, less noisy, and causes less discomfort. With this device repeated measurements can be made without causing stress or discomfort, and without disturbing sleep. The arterial pressure measurement obtained using this device was reliable and reproducible. In some patients certain symptoms, possibly due to phaeochromocytoma, had been observed for several years before the study, although hypertension had not been identified. While these patients had consistently high circulating catecholamine levels, nocturnal falls in blood pressure were clearly documented. This suggests that plasma catecholamines released from the phaeochromocytoma, though excessive, may be of less physiological importance than other regulatory mechanisms concerned with circadian fluctuation of blood pressure, e.g. the sympathetic nervous system and/or hypothalamo-pituitary-adrenal system. This new device has proved to be a reliable means of monitoring long-term blood pressure and is useful in the diagnosis of paroxysmal hypertension in patients with phaeochromocytoma.
一种用于间接测量动脉血压的新型便携式设备已成功应用于检测嗜铬细胞瘤患者的阵发性高血压和血压的昼夜波动。该设备采用容积示波技术，配备微处理器，可对人体手指的间接血压进行长期自动监测。与传统的臂带式全自动便携式设备相比，我们目前的设备更轻、噪音更小，且不适感更小。使用该设备可以进行重复测量，不会引起压力或不适，也不会干扰睡眠。使用该设备获得的动脉压测量结果可靠且可重复。在一些患者中，尽管在研究前未发现高血压，但在研究前几年就观察到了某些可能由嗜铬细胞瘤引起的症状。虽然这些患者的循环儿茶酚胺水平一直很高，但夜间血压下降情况有明确记录。这表明，嗜铬细胞瘤释放的血浆儿茶酚胺虽然过量，但可能比与血压昼夜波动有关的其他调节机制（如交感神经系统和/或下丘脑 - 垂体 - 肾上腺系统）的生理重要性更低。这种新设备已被证明是监测长期血压的可靠手段，对嗜铬细胞瘤患者阵发性高血压的诊断很有用。
