哥本哈根孕妇中耐甲氧西林金黄色葡萄球菌（MRSA）鼻腔携带率。
Prevalence of MRSA nasal carriage among pregnant women in Copenhagen.
机构信息
Department of Clinical Microbiology, Copenhagen University Hospital Hvidovre, Hvidovre, Denmark.
Department of Pediatrics and Adolescent Medicine, Copenhagen University Hospital Hvidovre, Hvidovre, Denmark.
出版信息
PLoS One. 2021 Jan 29;16(1):e0246343. doi: 10.1371/journal.pone.0246343. eCollection 2021.
Abstract
BACKGROUND
Methicillin resistant Staphylococcus aureus (MRSA) frequently causes outbreaks in neonatal intensive care units (NICUs). It is believed that MRSA predominantly enters the NICU with MRSA colonized parents. In Denmark, 27 MRSA NICU outbreaks have been registered between 2008 and 2019.
AIM
The aim of this study was to determine the prevalence of MRSA nasal carriage in pregnant women in Copenhagen and to clarify if MRSA screening during pregnancy could add to the prevention of NICU outbreaks.
METHODS
All pregnant women 18 years or older were offered MRSA nasal screening at their first midwife visit between 13 and 20 weeks of gestation.
RESULTS
1778 pregnant women were included, two (0.11%) carried MRSA in the nose.
CONCLUSION
Infants of the two MRSA positive women were not admitted to a NICU and therefore the screening had no impact on NICU outbreaks. The low prevalence of MRSA found in this study does not justify MRSA screening of all pregnant women in Denmark.
摘要
背景
耐甲氧西林金黄色葡萄球菌（MRSA）经常在新生儿重症监护病房（NICU）引发爆发。人们认为，MRSA 主要是通过定植了 MRSA 的父母进入 NICU 的。在丹麦，2008 年至 2019 年间共登记了 27 起 NICU 爆发的 MRSA 事件。
目的
本研究旨在确定哥本哈根孕妇中耐甲氧西林金黄色葡萄球菌鼻腔携带率，并阐明孕妇怀孕期间的 MRSA 筛查是否有助于预防 NICU 爆发。
方法
所有 18 岁或以上的孕妇均在妊娠 13 至 20 周的第一次助产士就诊时接受 MRSA 鼻腔筛查。
结果
共纳入 1778 名孕妇，其中 2 名（0.11%）鼻部分离出 MRSA。
结论
这两名携带 MRSA 的孕妇的婴儿未被收治到 NICU，因此该筛查对 NICU 爆发没有影响。本研究发现的 MRSA 低流行率表明，丹麦没有理由对所有孕妇进行 MRSA 筛查。
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