• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Characterization of SARS-CoV-2-specific antibodies in COVID-19 patients reveals highly potent neutralizing IgA.

作者信息

Zeng Weihong, Ma Huan, Ding Chengchao, Yang Yunru, Sun Yong, Huang Xiaoxue, He Weihuang, Xiang Yan, Gao Yong, Jin Tengchuan

机构信息

Department of Obstetrics and Gynecology, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, China.

Hefei National Laboratory for Physical Sciences at Microscale, CAS Key Laboratory of Innate Immunity and Chronic Disease, Division of Life Sciences and Medicine, School of Basic Medical Sciences, University of Science and Technology of China, Hefei, Anhui, China.

出版信息

Signal Transduct Target Ther. 2021 Jan 29;6(1):35. doi: 10.1038/s41392-021-00478-7.

DOI:10.1038/s41392-021-00478-7
PMID:33514692
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7844101/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a70e/7846583/5085e4c31586/41392_2021_478_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a70e/7846583/5085e4c31586/41392_2021_478_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a70e/7846583/5085e4c31586/41392_2021_478_Fig1_HTML.jpg

相似文献

1
Characterization of SARS-CoV-2-specific antibodies in COVID-19 patients reveals highly potent neutralizing IgA.对新冠病毒肺炎患者中新冠病毒2型特异性抗体的表征揭示了高效中和性IgA。
Signal Transduct Target Ther. 2021 Jan 29;6(1):35. doi: 10.1038/s41392-021-00478-7.
2
Neutralizing SARS-CoV-2.中和 SARS-CoV-2
Elife. 2020 Dec 15;9:e64496. doi: 10.7554/eLife.64496.
3
Commercial immunoglobulin products contain cross-reactive but not neutralizing antibodies against SARS-CoV-2.商业免疫球蛋白产品含有针对严重急性呼吸综合征冠状病毒2（SARS-CoV-2）的交叉反应性但无中和作用的抗体。
J Allergy Clin Immunol. 2021 Mar;147(3):876-877. doi: 10.1016/j.jaci.2020.12.003. Epub 2020 Dec 17.
4
Anti-Spike Mucosal IgA Protection against SARS-CoV-2 Omicron Infection.抗刺突黏膜IgA对SARS-CoV-2奥密克戎感染的保护作用。
N Engl J Med. 2022 Oct 6;387(14):1333-1336. doi: 10.1056/NEJMc2209651. Epub 2022 Sep 14.
5
Molecular deconvolution of the neutralizing antibodies induced by an inactivated SARS-CoV-2 virus vaccine.一种灭活的严重急性呼吸综合征冠状病毒2（SARS-CoV-2）病毒疫苗诱导的中和抗体的分子去卷积分析
Protein Cell. 2021 Oct;12(10):818-823. doi: 10.1007/s13238-021-00840-z. Epub 2021 Apr 28.
6
Antibody affinity maturation and plasma IgA associate with clinical outcome in hospitalized COVID-19 patients.抗体亲和力成熟和血浆 IgA 与住院 COVID-19 患者的临床结局相关。
Nat Commun. 2021 Feb 22;12(1):1221. doi: 10.1038/s41467-021-21463-2.
7
Rapid decline of neutralizing antibodies against SARS-CoV-2 among infected healthcare workers.感染医护人员体内针对 SARS-CoV-2 的中和抗体迅速下降。
Nat Commun. 2021 Feb 8;12(1):844. doi: 10.1038/s41467-021-21111-9.
8
Comparative analyses of SARS-CoV-2 binding (IgG, IgM, IgA) and neutralizing antibodies from human serum samples.比较分析来自人类血清样本的 SARS-CoV-2 结合抗体（IgG、IgM、IgA）和中和抗体。
J Immunol Methods. 2021 Feb;489:112937. doi: 10.1016/j.jim.2020.112937. Epub 2020 Nov 28.
9
Measuring cellular and humoral immunogenicity of a SARS-CoV-2 mRNA vaccine (BNT126b2) in patients on maintenance haemodialysis.评估严重急性呼吸综合征冠状病毒2（SARS-CoV-2）信使核糖核酸（mRNA）疫苗（BNT126b2）在维持性血液透析患者中的细胞免疫原性和体液免疫原性。
EBioMedicine. 2021 Sep;71:103567. doi: 10.1016/j.ebiom.2021.103567. Epub 2021 Aug 26.
10
Distinct neutralization profile of spike variants by antibodies induced upon SARS-CoV-2 infection or vaccination.SARS-CoV-2感染或疫苗接种诱导产生的抗体对刺突蛋白变体的独特中和谱。
Am J Hematol. 2022 Jan 1;97(1):E3-E7. doi: 10.1002/ajh.26380. Epub 2021 Nov 5.

引用本文的文献

1
Lactoferrin and SIgA Concentrations in Human Milk of SARS-CoV-Infected Mothers-Polish Cohort Study.新冠病毒感染母亲母乳中的乳铁蛋白和分泌型免疫球蛋白A浓度——波兰队列研究
Nutrients. 2025 May 28;17(11):1840. doi: 10.3390/nu17111840.
2
Natural Infection of Omicron BA.5.2 in Patients Provides Broad Immune Responses Against SARS-CoV-2.奥密克戎BA.5.2在患者中的自然感染可引发针对严重急性呼吸综合征冠状病毒2（SARS-CoV-2）的广泛免疫反应。
Microorganisms. 2025 Mar 26;13(4):746. doi: 10.3390/microorganisms13040746.
3
Immunoglobulin A response to SARS-CoV-2 infection and immunity.
针对严重急性呼吸综合征冠状病毒2（SARS-CoV-2）感染的免疫球蛋白A反应与免疫
Heliyon. 2024 Jan 3;10(1):e24031. doi: 10.1016/j.heliyon.2024.e24031. eCollection 2024 Jan 15.
4
Advances in nanobiosensors during the COVID-19 pandemic and future perspectives for the post-COVID era.新冠疫情期间纳米生物传感器的进展及后新冠时代的未来展望。
Nano Converg. 2024 Jan 11;11(1):3. doi: 10.1186/s40580-023-00410-5.
5
Intramuscular mRNA BNT162b2 vaccine against SARS-CoV-2 induces neutralizing salivary IgA.肌肉内注射 mRNA BNT162b2 疫苗可诱导针对 SARS-CoV-2 的唾液中和性 IgA。
Front Immunol. 2023 Jan 30;13:933347. doi: 10.3389/fimmu.2022.933347. eCollection 2022.
6
Characterization of Systemic and Mucosal Humoral Immune Responses to an Adjuvanted Intranasal SARS-CoV-2 Protein Subunit Vaccine Candidate in Mice.小鼠中一种佐剂鼻内接种的SARS-CoV-2蛋白亚单位候选疫苗的全身和粘膜体液免疫反应特征
Vaccines (Basel). 2022 Dec 23;11(1):30. doi: 10.3390/vaccines11010030.
7
Screening and Characterization of Shark-Derived VNARs against SARS-CoV-2 Spike RBD Protein.对 SARS-CoV-2 刺突 RBD 蛋白的鲨鱼衍生 VNAR 进行筛选和表征。
Int J Mol Sci. 2022 Sep 18;23(18):10904. doi: 10.3390/ijms231810904.
8
Towards Control and Oversight of SARS-CoV-2 Diagnosis and Monitoring through Multiplexed Quantitative Electroanalytical Immune Response Biosensors.通过多重定量电分析免疫反应生物传感器实现对SARS-CoV-2诊断和监测的控制与监督
Angew Chem Weinheim Bergstr Ger. 2022 Jul 11;134(28):e202203662. doi: 10.1002/ange.202203662. Epub 2022 May 24.
9
Local and Systemic Immunity Are Impaired in End-Stage-Renal-Disease Patients Treated With Hemodialysis, Peritoneal Dialysis and Kidney Transplant Recipients Immunized With BNT162b2 Pfizer-BioNTech SARS-CoV-2 Vaccine.血液透析、腹膜透析和接受 BNT162b2 辉瑞-生物科技 SARS-CoV-2 疫苗免疫的肾移植患者的局部和全身免疫受损。
Front Immunol. 2022 Jul 22;13:832924. doi: 10.3389/fimmu.2022.832924. eCollection 2022.
10
Acute Surge of Atypical Memory and Plasma B-Cell Subsets Driven by an Extrafollicular Response in Severe COVID-19.严重 COVID-19 中滤泡外反应驱动的非典型记忆和浆细胞亚群的急性激增。
Front Cell Infect Microbiol. 2022 Jul 8;12:909218. doi: 10.3389/fcimb.2022.909218. eCollection 2022.