Zhu Yafei, Bao Mengyao, Jiang Miaomiao, Chang Jincai, Cui Jianzhong
College of Sciences, North China University of Science and Technology, Tangshan, 063210, Hebei, China.
Department of Neurosurgery, Tangshan Gongren Hospital, Tangshan, 063000, Hebei, China.
Vis Comput Ind Biomed Art. 2021 Jan 30;4(1):3. doi: 10.1186/s42492-020-00068-4.
The elimination of intracranial hematomas has received widespread attention and the interactions between hemolytic agents and hematomas have become a hot research topic. In this study, we used the Navier-Stokes equation to describe the flow control equation for hemolytic agents in a tube and used Fick's law and the Maxwell-Stefan diffusion theory to describe the diffusion and mass transfer of hemolytic agents and hematomas. The physical fields and initial boundary conditions were set according to the parametric properties of the fluid and drainage tube. The COMSOL Multiphysics software was used to simulate the streamline distribution of hemolytic agents in a bifurcated drainage tube. Additionally, the diffusion behaviors of the hemolytic agents into hematomas were simulated and visual analysis of coupled multiphysics was performed to realize the digitization and visualization of engineering fluid problems and contribute to the field of medical engineering.
颅内血肿的清除受到广泛关注，溶血剂与血肿之间的相互作用已成为热门研究课题。在本研究中，我们使用纳维 - 斯托克斯方程来描述溶血剂在管道中的流动控制方程，并使用菲克定律和麦克斯韦 - 斯蒂芬扩散理论来描述溶血剂与血肿的扩散和传质。根据流体和引流管的参数特性设置物理场和初始边界条件。使用COMSOL Multiphysics软件模拟溶血剂在分叉引流管中的流线分布。此外，模拟了溶血剂向血肿内的扩散行为，并进行了多物理场耦合的可视化分析，以实现工程流体问题的数字化和可视化，为医学工程领域做出贡献。
