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无高血压或子痫前期病史的产后高血压患者再次就诊的危险因素。

Risk factors for re-presentation for postpartum hypertension in patients without a history of hypertension or preeclampsia.

机构信息

Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, Cedars-Sinai Medical Center, Los Angeles, CA.

Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, Cedars-Sinai Medical Center, Los Angeles, CA.

出版信息

Am J Obstet Gynecol MFM. 2021 Mar;3(2):100297. doi: 10.1016/j.ajogmf.2020.100297. Epub 2020 Dec 15.

Abstract

BACKGROUND

Re-presentation for evaluation of hypertension following discharge after delivery is common. However, a subset of patients who re-present for evaluation of postpartum hypertension do not have a history of hypertension. Identification of those at risk may help guide postpartum management and prevent re-presentations to the hospital.

OBJECTIVE

This study aimed to establish risk factors for re-presentation for hypertension within 30 days of discharge after delivery in patients without a history of hypertension compared with women who did not re-present and to distinguish from risk factors for re-presentation for another reason.

STUDY DESIGN

Subjects were identified through data extraction from a single institution between January 2012 and December 2018. We included subjects without an International Classification of Diseases, Ninth Revision or International Classification of Diseases, Tenth Revision code for (1) chronic hypertension or (2) a hypertensive disorder of pregnancy during their delivery encounter who re-presented to the hospital within 30 days. Thus, the re-presentation group was divided into the following 2 groups: those who re-presented for hypertension and those who re-presented for any other reason. Each re-presentation group was compared with the cohort of patients who delivered within the study window and did not re-present using the Student t test or Wilcoxon tests for continuous variables and chi-square or Fisher's exact tests for categorical variables. Multivariable regression was also performed on all potentially important risk factors.

RESULTS

Factors that emerged as uniquely significant in the re-presentation group for hypertension were maternal age of ≥40 years and antenatal prescription of low-dose aspirin. Black race and body mass index of ≥30 kg/m, although significant in both re-presentation groups, were more strongly predictive of re-presentation for hypertension. These factors remained independently significant when compared with each other in a multivariable analysis.

CONCLUSION

There are identifiable risk factors for postpartum re-presentation for hypertension in patients without a history of hypertension. Upon discharge, providers may consider close blood pressure monitoring and follow-up in patients who have any of the following risk factors: age of ≥40 years, black race, body mass index of ≥30 kg/m, or those who were prescribed low-dose aspirin in pregnancy.

摘要

背景

产后出院后评估高血压的再表现很常见。然而,一部分再表现为产后高血压的患者没有高血压病史。识别这些高危患者可能有助于指导产后管理并防止再次住院。

目的

本研究旨在确定与未再表现的患者相比,无高血压病史的产后 30 天内因高血压再次就诊的患者的危险因素,并将其与因其他原因再表现的危险因素区分开来。

研究设计

通过从 2012 年 1 月至 2018 年 12 月期间从单一机构提取数据来确定研究对象。我们纳入了在分娩期间没有国际疾病分类第 9 版或第 10 版(1)慢性高血压或(2)妊娠期高血压疾病编码的患者,这些患者在 30 天内再次到医院就诊。因此,再表现组分为以下 2 组:因高血压再表现的患者和因其他任何原因再表现的患者。使用 Student t 检验或 Wilcoxon 检验比较每个再表现组与研究窗口内分娩且未再表现的患者的连续变量,使用卡方检验或 Fisher 确切概率法比较分类变量。对所有潜在的重要危险因素也进行了多变量回归分析。

结果

在因高血压再表现的患者中,唯一显著的因素是母亲年龄≥40 岁和产前低剂量阿司匹林的处方。黑人和体重指数≥30 kg/m2,尽管在两个再表现组中都有显著意义,但对因高血压再表现的预测作用更强。在多变量分析中,与其他因素相比,这些因素仍然具有显著意义。

结论

在无高血压病史的患者中,产后因高血压再表现有可识别的危险因素。出院时,对于有以下任何危险因素的患者,医生可能需要密切监测血压并进行随访:年龄≥40 岁、黑种人、体重指数≥30 kg/m2,或在孕期服用低剂量阿司匹林。

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