Norman J C, Cooley D A, Igo S R, Hibbs C W, Johnson M D, Bennett J G, Fuqua J M, Trono R, Edmonds C H
J Thorac Cardiovasc Surg. 1977 Nov;74(5):709-20.
To define more clearly a salvageable patient for possible utilization of a left ventricular assist device prior to multiple organ failure and irretrievability during postcardiotomy intra-aortic balloon pumping (IABP), we made prospective and retrospective analyses to determine prognostic indices for survival. Serial left ventricular function curves (IABP on-off), scoring methods, hemodynamic and renal function tracking trajectories, survival versus nonsurvival data envelopes, and classification methods were developed and used. All patients requiring postcardiotomy IABP support who were in Class A survived; 80 percent of the patients in Class B survived. All patients who remained in Class C for 12 hours or more following operation with IABP support died. These preliminary analyses suggest that the postcardiotomy IABP-supported patient with a score of less than 6 who remains in Class C for 12 hours or more is at the highest possible risk and is a probably candidate for more effective support with a left ventricular assist device.
为了更明确地界定在多器官功能衰竭及心脏术后主动脉内球囊反搏(IABP)期间病情不可挽回之前,可通过使用左心室辅助装置进行抢救的患者,我们进行了前瞻性和回顾性分析以确定生存的预后指标。我们制定并使用了连续左心室功能曲线(IABP开启-关闭)、评分方法、血流动力学和肾功能跟踪轨迹、生存与非生存数据包络以及分类方法。所有需要心脏术后IABP支持且属于A类的患者均存活;B类患者中80%存活。所有在IABP支持下术后在C类状态持续12小时或更长时间的患者均死亡。这些初步分析表明,心脏术后接受IABP支持、评分低于6分且在C类状态持续12小时或更长时间的患者处于极高风险,可能是使用左心室辅助装置进行更有效支持的候选对象。