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Negligible risk of hepatocellular carcinoma in chronic hepatitis B patients in immune-tolerant phase: Myth or fact.

作者信息

Yip Terry Cheuk-Fung, Wong Grace Lai-Hung, Wong Vincent Wai-Sun

机构信息

Medical Data Analytics Centre, The Chinese University of Hong Kong, Hong Kong SAR, China.

Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong SAR, China.

出版信息

Clin Mol Hepatol. 2021 Apr;27(2):273-277. doi: 10.3350/cmh.2021.0019. Epub 2021 Feb 1.

DOI:10.3350/cmh.2021.0019
PMID:33517606
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8046624/
Abstract
摘要

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本文引用的文献

1
Negligible risks of hepatocellular carcinoma during biomarker-defined immune-tolerant phase for patients with chronic hepatitis B.对于慢性乙型肝炎患者，生物标志物定义的免疫耐受期发生肝细胞癌的风险可忽略不计。
Clin Mol Hepatol. 2021 Apr;27(2):295-304. doi: 10.3350/cmh.2020.0216. Epub 2020 Dec 3.
2
Negligible HCC risk during stringently defined untreated immune-tolerant phase of chronic hepatitis B.慢性乙型肝炎严格定义的未经治疗免疫耐受期内 HCC 风险可忽略不计。
Eur J Intern Med. 2021 Feb;84:68-73. doi: 10.1016/j.ejim.2020.10.022. Epub 2020 Dec 4.
3
Repeated FIB-4 measurements can help identify individuals at risk of severe liver disease.重复的 FIB-4 检测有助于识别发生严重肝脏疾病风险的个体。
J Hepatol. 2020 Nov;73(5):1023-1029. doi: 10.1016/j.jhep.2020.06.007. Epub 2020 Jul 1.
4
KASL clinical practice guidelines for management of chronic hepatitis B.《慢性乙型肝炎管理的KASL临床实践指南》
Clin Mol Hepatol. 2019 Jun;25(2):93-159. doi: 10.3350/cmh.2019.1002. Epub 2019 Jun 12.
5
Improvement in enhanced liver fibrosis score and liver stiffness measurement reflects lower risk of hepatocellular carcinoma.增强纤维化评分和肝硬度测量的改善反映了肝细胞癌风险的降低。
Aliment Pharmacol Ther. 2019 Jun;49(12):1509-1517. doi: 10.1111/apt.15269. Epub 2019 Apr 25.
6
Unmet need in chronic hepatitis B management.慢性乙型肝炎管理中的未满足需求。
Clin Mol Hepatol. 2019 Jun;25(2):172-180. doi: 10.3350/cmh.2018.0106. Epub 2019 Feb 12.
7
Normal on-treatment ALT during antiviral treatment is associated with a lower risk of hepatic events in patients with chronic hepatitis B.抗病毒治疗期间的正常 ALT 水平与慢性乙型肝炎患者发生肝脏事件的风险降低相关。
J Hepatol. 2018 Oct;69(4):793-802. doi: 10.1016/j.jhep.2018.05.009.
8
Update on prevention, diagnosis, and treatment of chronic hepatitis B: AASLD 2018 hepatitis B guidance.慢性乙型肝炎的预防、诊断和治疗最新进展：美国肝病研究学会2018年乙型肝炎指南
Hepatology. 2018 Apr;67(4):1560-1599. doi: 10.1002/hep.29800.
9
Management of chronic hepatitis B patients in immunetolerant phase: what latest guidelines recommend.慢性乙型肝炎病毒感染者免疫耐受期的管理：最新指南推荐。
Clin Mol Hepatol. 2018 Jun;24(2):108-113. doi: 10.3350/cmh.2017.0068. Epub 2018 Jan 22.
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High risk of hepatocellular carcinoma and death in patients with immune-tolerant-phase chronic hepatitis B.免疫耐受期慢性乙型肝炎患者发生肝细胞癌和死亡的风险较高。
Gut. 2018 May;67(5):945-952. doi: 10.1136/gutjnl-2017-314904. Epub 2017 Oct 21.