Species Restoration Technology Institute of Korea National Park Service, Gurye 57616, Republic of Korea.
Department of Veterinary Clinical Sciences and Research Institute for Veterinary Science, College of Veterinary Medicine, Seoul National University, Gwanak-gu, Seoul 08826, Republic of Korea,
J Zoo Wildl Med. 2019 Sep;50(3):718-722. doi: 10.1638/2017-0160.
The present study evaluated the effects of fluoxetine on decreasing stereotypic behaviors in Asiatic black bears (ABB). Four captive ABB exhibiting stereotypic behaviors were administered fluoxetine (0.25-1 mg/ kg orally every 24 hr) for 91 days. The animals were monitored twice weekly for 213 days (April to October) using a scan sampling method (preadministration, 30 day; administration, 91 days; postadministration, 92 days). Five blood samples were collected from the jugular vein of each bear for serum chemistry analysis (one during preadministration; two each during administration and postadministration periods). Fluoxetine was safe and effective in decreasing stereotypies, but it may be difficult to decrease long-established stereotypies in ABB using fluoxetine alone. To decrease stereotypies in ABB effectively, it is necessary to identify underlying problems that contribute to stereotypic behavior and apply comprehensive interventions that can include fluoxetine treatment.
本研究评估了氟西汀对减少亚洲黑熊刻板行为的影响。四只表现出刻板行为的圈养亚洲黑熊被给予氟西汀（0.25-1 毫克/千克，每天口服两次）91 天。在 213 天（4 月至 10 月）的时间里，使用扫描采样法（给药前、30 天；给药期、91 天；给药后、92 天）每周对动物进行两次监测。从每只熊的颈静脉采集五份血液样本进行血清化学分析（给药前一次；给药期和给药后各两次）。氟西汀安全有效，可减少刻板行为，但单独使用氟西汀可能难以减少亚洲黑熊的长期刻板行为。为了有效地减少亚洲黑熊的刻板行为，有必要确定导致刻板行为的潜在问题，并应用综合干预措施，其中可能包括氟西汀治疗。
